Aortic valvular insufficiency caused by syphilis cannot be differentiated by murmur or other clinical characteristics from other causes of aortic insufficiency, and the aid of serological tests is often sought. Routine serological tests for syphilis, such as the VDRL slide test, which utilize cardiolipin antigens, are reactive in only 75 to 95 per cent. of patients with cardiovascular syphilis ...

OBJECTIVE To determine the efficacy of single-dose benzathine penicillin G in infants at high risk of congenital syphilis. DESIGN Randomised study comparing benzathine penicillin with no therapy. SETTING Peninsula Maternal and Neonatal Service, Cape Town. SUBJECTS Asymptomatic infants born to mothers with untreated syphilis whose VDRL titre was 32 or more. OUTCOME MEASURES The number of...

Introdução. A neurossífilis é uma manifestação pouco frequente da infecção do sistema nervoso central (SNC) pelo Treponema pallidum. Casos. Nós relatamos três casos de neurossífilis. O caso 1 apresentavase com envolvimento ocular: atrofia ótica à direita e neurite ótica à esquerda; o caso 2 uma forma meningovascular com Acidente Vascular Cerebral isquêmico; e o caso 3, uma forma meníngea, tinha...

Ten sporadic cases of venereal spirochaetosis, caused by Treponema paraluis-cuniculi, were seen in New Zealand white rabbits in two years. An equal number of males and females were affected. Females tended to have milder clinical signs than males. Lesions were usually found on the prepuce in males and the vulva in females, although the anus and skin of the perineum were also affected. Facial le...

One serum and three plasma samples were obtained from each of 125 normal individuals and from 140 patients with treated or untreated syphilis. Serum samples were tested by the Venereal Disease Research Laboratory (VDRL) test and by the Reagin Screen Test (RST). Plasma specimens were tested only with the RST. When tested within 24 h after collection, all specimens from normal individuals were no...

Objectives: Veneral Disease Research Laboratory (VDRL) test is an important screening tool for syphilis in pregnancy (because of adverse outcomes, particularly congenital {CS}) and can be combined with the placental histopathological examination diagnosis CS. Thus, we aimed to compare VDRL results from HIV-positive/HIV-negative pregnant women relevant historical data perinatal/placental finding...

OBJECTIVE A Cross Sectional population based serological studies was conducted to determine the prevalence and associated risk factors for syphilis women with recurrent miscarriages. METHODS Patient's 5ml whole blood was collected through venepuncture technique. Data were collected by all women answered a questionnaire and by investigating blood sample VDRL test and FTA-ABS test. The study wa...