1. What is a Hypercar® vehicle? 2. How could Hypercar® vehicles attain such dramatically improved fuel economy? 3. Would there be tradeoffs in performance or styling? 4. Why a hybrid-electric instead of a battery-electric vehicle? 5. What fuels would Hypercar® vehicles use? 6. Are fuel cells being considered in Hypercar® vehicles? 7. Why advanced composites? 8. Would Hypercar® vehicles be safe?...

In distribution networks, failure to smooth the load curve leads to voltage drop and power quality loss. In this regard, electric vehicle batteries can be used to smooth the load curve. However, to persuade vehicle owners to share their vehicle batteries, we must also consider the owners' profits. A challenging problem is that existing methods do not take into account the vehicle owner demands ...

Transient prehypertensive treatment (TPT) causes prolonged antihypertensive and cardioprotective effects. Reduced angiotensin sensitivity has been attributed to those effects. We hypothesize that prehypertensive preconditioning by angiotensin II type 1 receptor (AT1R) blockade improves cardiovascular protection of late-onset AT1R blockade in a model of spontaneous hypertensive heart-failure rat...

In this paper, the 1/4 vehicle model have been simulated. The vehicle body acceleration using optimal control has been optimized. The vehicle ride comfort is achieved by using robust control, and it has been compared with optimal control. The active suspension can help the vehicle to have a good dynamic behavioral. In this paper, two degrees of freedom dynamic vibration model of a general ve...

BSF468248 is a novel potent complement C1 inhibitor. To determine whether BSF468248 is effective against focal cerebral ischemia, we evaluated the change of cerebral blood flow (CBF) and infarction volume using a photochemically-induced cortical vein occlusion model in rats in blind studies. In 22 Wistar rats, two adjacent cortical veins were occluded by photochemical thrombosis and fiberoptic ...

trauma during pregnancy is remarkably common, motor vehicle crashes are cause of hospitalized trauma during pregnancy. trauma occurs in 5% of pregnancies that appropriate high proportion of maternal and fetal mortality. motor vehicle crashes, falls, assaults, including domestic violence, are all important mechanisms of injury. motor vehicle accidents account for more than 50% of all traumas dur...

Delta-9-tetrahydrocannabinol (Δ9-THC), the psychoactive component of marijuana, is known to suppress the immune responses to bacterial, viral and protozoan infections, but its effects on fungal infections have not been studied. Therefore, we investigated the effects of chronic Δ9-THC treatment on mouse resistance to systemic Candida albicans (C. albicans) infection. To determine the outcome of ...

A well-known challenge in computable general equilibrium (CGE) models is to maintain correspondence between the forecasted economic and physical quantities over time. Maintaining such a correspondence is necessary to understand how economic forecasts reflect, and are constrained by, relationships within the underlying physical system. This work develops a method for projecting global demand for...

BACKGROUND Green tea catechins seem to contribute toward reducing body weight and fat. OBJECTIVE We aimed to investigate whether chronic administration of (-)-epigallocatechin-3-gallate (EGCG), the most abundant catechin of green tea, reduces weight gain in spontaneously hypertensive rats (SHR), an animal model of metabolic syndrome, by increasing motor activity and/or by altering gastrointes...

Stimulation of renal dopamine-1 (DA1) receptors for 3 hours produces an increase in renal plasma flow and sustained natriuresis. The present study was designed to assess the response of renal hemodynamic and tubular function to long-term DA1 receptor stimulation. Fenoldopam, a selective DA1 receptor agonist, was infused intravenously for 24 hours in 10 normal male subjects in metabolic balance ...