This paper describes the anatomic spiral arrangement of the cardiac interventricular septum that results in a twisting action that contributes to the forceful ejection of blood from both ventricles during systole. Right ventricular (RV) dysfunction seen in various clinical settings is discussed with reference to the septum and its mechanism of function. The role of the septum in the interdepend...

There is still disagreement concerning the precise nature of the anterior ventricular chamber in "tricuspid atresia". Some argue that it is a right ventricle, while our own previous studies have suggested it is comparable to the outlet chamber seen in classical "single ventricle". We have compared the morphology of the anterior ventricular chambers in 48 examples of tricuspid atresia (absent ri...

Hypertrophic obstructive cardiomyopathy (HOCM), the cause of which is unknown, is a heart disease characterized by obstruction of the left ventricular outflow tract and an increase in interventricular septum thickness. Octreotide, a synthetic analogue of somatostatin, was administered subcutaneously to 15 patients for 6 months in order to determine its efficacy in HOCM. Echocardiographic examin...

INTRODUCTION Chronic stimulation of the right ventricle with pacemaker is associated with ventricular dyssynchrony and loss of contractility, even in subjects without previous dysfunction. In these patients, there is a debate of which pacing site is less associated with loss of ventricular function. OBJECTIVE To compare pacemaker-induced dyssynchrony among different pacing sites in right vent...

The left and right ventricular function of the heart are influenced by the complex structure of the ventricular septum. The cyclic variation of ultrasonic backscatter over the cardiac cycle is known to be sensitive to both structural and functional characteristics of the myocardium. The objective of this study was to investigate differences in the measured magnitude and normalized delay of cycl...

A 68-year-old man with cardiomyopathy out of proportion to ischemic heart disease, previous coronary artery bypass grafting, and a biventricular implantable cardioverterdefibrillator presented with incessant ventricular tachycardia (VT) refractory to amiodarone and previous ablation attempts. Recent nuclear stress testing demonstrated no evidence of ischemia and a small area of scar at the infe...

OBJECTIVES Increasing evidence suggests that left ventricular remodeling is associated with a shift from fatty acid to glucose metabolism for energy production. The aim of this study was to determine whether left ventricular remodeling with and without late-onset heart failure after myocardial infarction is associated with regional changes in the expression of regulatory proteins of glucose or ...

• Variation in cardiac position lias been frequently suggested as a principal cause for the wide contrast in configuration of electrocardiograms.^ In contrast, both postmortem and biplane angiographic examinations have suggested that there is relatively little actual anatomical variation in the position of the heart or more particularly of the interventricular septum in healthy or diseased man....

AIMS To analyze the paced QRS duration in various septal positions of the right ventricular leads and with different paced QRS vectors. To use the results to assess parameters suggesting the optimal site for right ventricular pacing. METHODS AND RESULTS A total of 609 patients with leads implanted in the right ventricular septum were classified using fluoroscopy in the lateral view (the prima...

background: patients suffering from major beta thalassemia need frequent blood transfusions and, if not treated well, would be at risk of heart dysfunction. this study was performed to determine the diagnostic value of electrocardiography versus echocardiography in measuring the left ventricular mass index in these patients. methods: between july 2010 and june 2011, 82 asymptomatic patients ove...