Fifteen patients with intestinal villous atrophy, but simultaneously negative results of antiendomysial antibodies (EMA) were studied. Two patients were finally diagnosed as having coeliac disease. The predictive value of negative results of EMA assessment in children suspected of coeliac disease is high, approaching 86.7%.

A patient presented with subtotal villous atrophy and a malignant duodenal tumour of uncertain histogenesis. He was successfully treated by resection and chemotherapy and the small bowel mucosa recovered on a gluten free diet. The tumour was diagnosed at upper gastrointestinal endoscopy when barium studies and abdominal computed tomography were normal, thus making this one of the earliest coeli...

BACKGROUND Coeliac disease (CD), characterised by the presence of villous atrophy (VA) in the small intestine, is associated with increased mortality, but it is unknown if mortality is influenced by mucosal recovery. AIMS To determine whether persistent VA is associated with mortality in CD. METHODS Through biopsy reports from all pathology departments (n = 28) in Sweden, we identified 7648...

INTRODUCTION refractory iron-deficiency anemia has a multifactorial origin related to various gastrointestinal conditions, with celiac disease plus malabsorption and IBD together with isolated gluten intolerance being most common. OBJECTIVES to determine the prevalence of serum, genetic, and histological markers for gluten intolerance, and to analyze the response to gluten withdrawal from the...

BACKGROUND Villous atrophy (VA) with intraepithelial lymphocytosis is the histological hallmark of coeliac disease (CD), but reported rates of mucosal recovery are variable. AIM To determine the impact of age and other demographic variables on the probability of persistent VA on follow-up biopsy. METHODS We identified patients with VA on duodenal histology at all 28 Swedish pathology depart...

fold increased risk of developing enterop− athy−associated T−cell lymphoma com− pared with the general population [1]. Early diagnosis is therefore required to improve their prospects. Indigo carmine chromoendoscopy highlights mucosal ir− regularities and improves the detection of malignant lesions [2]. Furthermore, it can delineate villous atrophy in celiac dis− ease [3]. This method is common...

BACKGROUND Celiac disease is associated with an increased risk of malignant lymphomas. The risk of lymphoproliferative malignancies in patients with small intestinal inflammation without villous atrophy and in patients with latent celiac disease is unknown. METHODS We performed a cohort study using duodenal and jejunal biopsy data that were collected from all 28 Swedish pathology departments ...

BACKGROUND & OBJECTIVES Aetiology of malabsorption syndrome (MAS) differs in tropical and temperate countries over time; clinical and laboratory parameters may differentiate between various causes. This study was undertaken to investigate the spectrum of MAS among Indian adults and to find out the features that may help to differentiate between TM and celiac disease. METHODS Causes of MAS, an...