background acute bacterial meningitis which is a pediatric emergency with high mortality and morbidity must be diagnosed and treat promptly. often diagnosis of bacterial meningitis from viral meningitis is difficult after some days. determination of some inflammatory mediators’ example il-6 and hs-crp were useful in differential diagnosis of bacterial and viral meningitis. objectives this study...

Background and Aims: Bovine viral diarrhea virus (BVDV) is considered as worldwide and economically significant infection. The aim of this study was to estimate prevalence of persistent bovine viral diarrhea infection (PI) in industrial dairies of Tehran and Alborz province, Iran. Materials and Methods: In this cross-sectional study, 102371 blood samples were collected from bovine of industria...

Cystic fibrosis (CF) is an autosomal recessive disorder caused by mutations in CFTR genes that affect chloride ion channel. The CF is a good nominee for gene therapy as the asymptomatic carriers are phenotypically normal, and the desired cells are accessible for vector delivery. Gene therapy shows promising effects involving the correction of gene or replacement of the mutant gene with the func...

Viruses are obligatory intracellular parasites that use cell proteins to take the control of the cell functions in order to accomplish their life cycle. Studying the viral-host interactions would increase our knowledge of the viral biology and mechanisms of pathogenesis. Studies on pathogenesis mechanisms of lyssaviruses, which are the causative agents of rabies, have revealed some important ho...

background and aims: inhibition of viral growth in coinfected cells with two different viruses has been described. this phenomenon known as viral interference can occur in several virus host systems such as interference of enterovirus infection on poliovirus vaccine strains. in this study we superinfected reovirus infected hela cells with poliovirus to determine if poliovirus can replicate in s...

Orf is a disease caused by parapoxviruses. Infection is transmitted to human from animals like sheep and goats, Herein, we report a 47- year- old man with fourteen lesions on different parts of his right hand, while usually the lesion is single and up to a maximum of ten lesions have been reported previously.

in the present study 220 diarrheal samples of children aged between 3-12 months and 100 samples from healthy individuals of the same age group reffered to Shiraz university hospitals were investigated for bacterial and viral agents.Electron microscopy methods were used for the viral investigations,while conventional techniques of bacteriology were used for isolation of bacterial agents.the prev...

The extract of licorice (Glycyrrhiza glabra L.) has been widely used for many centuries in the traditional Chinese medicine as native anti-allergic agent. Glycyrrhizin (GL), a triterpenoid-saponin, extracted from the roots of licorice is the most effective compound for inflammation and allergic diseases in human body. The biological and pharmacological studies revealed that GL possesses many ph...

conclusions the viral load in patients who suffer from cchf has a direct significant correlation with disease severity. viral load above 8.6 × 105 copies/ml on the first day of admission is a predictor of severe cchf. background crimean-congo hemorrhagic fever (cchf) is an endemic disease in south eastern of iran, especially in sistan and baluchestan province. cchf is a potentially fatal diseas...