Corona Virus Disease 2019 (COVID-19) caused by a novel coronavirus has spread all over the globe and become pandemic now. Until now several vaccines have come-up with limited efficacy for managing COVID-19. However, studies are still going on to find suitable therapeutic drugs which can target viral proteins or host receptor. Hence search plant-based anti-viral agents against SARS-CoV-2 is prom...

conclusions cd5l might be a useful biomarker for early diagnosis of hcc in hcv cirrhotic patients. lrg and hp α2 isoforms could be potential markers for distinguishing viral hcc. our results also further support the presence of varying molecules involved in hepatocarcinogenesis in hbv when compared with hcv infection. patients and methods two-dimensional polyacrylamide gel electrophoresis combi...

Radiolabeled Sendai virus was allowed to fuse with human erythrocytes and inside out vesicles were prepared from the erythrocyte membranes. Viral proteins incorporated into inside out vesicles were released from the membrane following treatment with various agents which perturb protein structure. Disruption products were analyzed by sucrose gradient centrifugation and sodium dodecyl sulfate-pol...

Coronavirus disease 2019 (Covid-19) is a very serious, contagious, and infectious that cause severe acute respiratory syndrome. It has four structural base proteins: envelope (E), nucleocapsid (N), membrane (M) spike (S) protein which responsible for the viral attachment, fusion, entry [1].

Matricellular proteins differ from other classical extracellular matrix proteins; for instance, they are transiently expressed as soluble proteins rather than being constitutively expressed in pathological conditions, such as acute viral infections. Accumulating studies have revealed that matricellular proteins, including osteopontin and tenascin-C, both of which interact with integrin heterodi...

There is an urgent need to establish large scale biopharmaceutical manufacturing capacity in Africa where the infrastructure for biologics production severely limited. Molecular farming, whereby pharmaceuticals are produced plants, offers a cheaper alternative mainstream expression platforms, and amenable rapid large-scale production. However, there several differences along plant protein secre...

MOTIVATION Viruses and developers of anti-inflammatory therapies share a common interest in proteins that manipulate the immune response. Large double-stranded DNA viruses acquire host proteins to evade host defense mechanisms. Hence, viral pirated proteins may have a therapeutic potential. Although dozens of viral piracy events have already been identified, we hypothesized that sequence diverg...