toxicity and drug resistance against pentavalent antimonials, medications of choice in treatment of leishmaniasis for more than 5 decades, have become important subjects globally. this study was a randomized, open labeled trial that was designed to determine efficacy and safety of imod as a novel herbal immunomodulator drug for treatment of canine visceral leishmaniasis (cvl).twenty healthy mon...

background: leishmaniasis is a tropical disease that is endemic in some areas of iran, including east azerbaijan . ifn-γ is one of the cytokines that triggers cell-mediated immunity, thus initiating elimination of the infection. this case-control study was performed to investigate the association between the polymorphism of the ifn-γ gene at the +874a/t locus and visceral leishmaniasis (vl). me...

background: although many studies had been conducted on various aspects of canine visceral leishmaniasis (cvl) in domestic dogs in the endemic areas of iran, investigations on cvl in wild canines are rare. methods : this is a cross-sectional study was conducted from december 2012 to 2013 in northeast of iran where human vl is endemic. wild canines were trapped around the areas where human vl ca...

background: dogs have been previously reported to be reservoirs of leishmania infantum as the etiological agent of human visceral leishmaniasis in iran. we report a case of canine visceral leishmaniasis (vl) caused by l. tropica from the north- west of iran where human visceral leishmaniasis is endemic. methods: the canine vl was initially screened by dipstick rk39 and direct agglutination test...

Three years after the first report of Lutzomyia longipalpis in Clorinda, Argentina, a border city near Asunción, Paraguay, the city was surveyed again. Lu. longipalpis was found clustered in the same neighbourhoods in 2007 as in 2004, even though the scattered distribution of canine visceral leishmaniasis was more related to the traffic of dogs through the border.

b ackground: mediterranean type of visceral leishmaniasis (vl) is present in different parts of iran. several studies have identified dogs as the main reservoirs of the vl caused by leishmania infantum in iran and other mediterranean regions. this study aimed to determine the seroprevalence of canine visceral leishmaniasis as animal reservoir host for human visceral leishmaniasis in boyer ahmad...

A Scottish girl acquired visceral leishmaniasis (kala-azar) while on holiday in Majorca. She presented with the infection, six months later, in Scotland. Because of inexperience with the disease and a degree of scepticism unnecessary investigations were carried out resulting in a delay in treatment.

Visceral leishmaniasis (VL), commonly known as kala-azar in Indian subcontinent is a major public health problem and >90% of cases are from India, Bangladesh, southern Sudan, Nepal and north-east Brazil. VL affects more than 1,00,000 persons every year in India and occurs epidemically and endemically in well-defined areas in the eastern parts of the country, mainly Bihar, West Bengal, the easte...

background: visceral leishmaniasis (vl) is caused by leishmania infantum in mediterranean basin and is an endemic disease in some parts of iran. canines are the main reservoirs of vl in most of the endemic areas. different serological methods have been introduced for diagnosis of canine visceral leishmaniasis (cvl). objective: in this survey a fucose-mannose ligand (fml) elisa, using native l. ...