Nuestro estudio se estructura en tres hipótesis intrínsecamente entrelazadas, que intentaremos confirmar a lo largo de éste: primer lugar, sostenemos relación al mundo como representación (Vorstellung) y voluntad (Wille), Schopenhauer apoya casi exclusivamente el Vedānta, mientras sus referencias “la negaci.n la voluntad” (die Verneigung des Willens zum Leben) hay una innegable alusión budismo....

A synbiotic is the combination of a microorganism shown (or thought) to have some beneficial effect when consumed (i.e. a probiotic) and a compound that specifically favours its growth (i.e. a prebiotic), having a synergistic effect when paired together. Many probiotic supplements are currently marketed as synbiotics. These products typically contain a combination of Bifidobacterium, Lactobacil...

Modulation of the human immune system has become the focus for several novel approaches to treat conditions related to immune dysregulation, chronic infections and oncology. The human gut microbiome is being recognized as a key factor associated with the innate immune response, and exploring it has resulted in the identification of leads for therapeutics to treat conditions related to immune dy...

Background: XB002 is an antibody-drug conjugate (ADC) composed of a high-affinity tissue factor (TF)-directed human monoclonal antibody conjugated to novel cytotoxic payload, ZymeLink Auristatin. TF, transmembrane protein, functions as FVIIa receptor, initiating the extrinsic coagulation cascade. TF also expressed in multiple tumor types. demonstrated antitumor activity pre-clinical studies acr...

Due to its clear benefits in the management of recurrent Clostridioides difficile infection, faecal microbiota transplantation (FMT) has been advocated by gastroenterological community as a non-postponable procedure be continuously delivered during COVID-19 pandemic.1Ianiro G Mullish BH Kelly CR et al.Screening transplant donors outbreak: suggestions for urgent updates from an international exp...

BackgroundTCR bispecific proteins (bsp) redirect polyclonal T cells to target intra/extracellular in cancer, as validated by tebentafusp (CD3×gp100 TCR) with a survival benefit metastatic uveal melanoma (HR 0.51). IMC-C103C is TCR bsp against MAGE-A4, cancer-testis antigen expressed several tumor types (eg, lung, ovarian, HNSCC, GEJ) but minimally normal tissue.MethodsHLA-A*02:01+ pts selected ...

Few seem to have difficulty in distinguishing between religious and secular institutions, yet there is widespread disagreement regarding what “religion” actually means. Indeed, some go so far as to question whether there is anything at all distinctive about religions. Hence, formulating a definition of “religion” that can command wide assent has proven to be an extremely difficult task. In this...