Virtual Endoscopy is a technique to explore hollow organs and anatomical cavities using 3D medical imaging and computer graphics. Virtual Endoscopy turns out to be a promising technique to improve, or even in some procedures substitute, real endoscopy. A real endoscopy is invasive and usually implies some risk for the patient. In the last decades, much research has been done in this field. This...

The present investigation was aimed at developing a novel colon targeted system of lornoxicam based on the use of a combination of pH dependent system (to prevent the premature release of drug in the upper GIT) and enzymatically degradation system (to ensure the specificity of drug release in the colon). The drug loaded guar gum microspheres prepared by emulsification cross-linking method were ...

Virtual endoscopy is a promising medical application of volume visualization techniques. A virtual endoscopy system requires high quality and perspective projection rendering, as well as real-time navigation. In this paper the generation of a cylindrical structure for tubular shaped organs (i.e. colon, aorta) is presented. This structure represents an approximation of the real organ. The cylind...

Three-dimensional (3D) cell culture methods are widely accepted as more physiologically relevant than conventional 2D cell culture methods and are believed to improve the prediction of drug candidates at an early stage of the drug development process. Here we describe the analysis of a spherical colon cancer microtissue model using the Operetta® High Content Imaging System. In vivo near-infrare...

Thin layers of tissue and residue are easily misclassified by current electronic cleansing methods for CT colonography. Thereby holes are introduced in the colon wall that hamper visualization and automated polyp detection. We present a thin layer model to detect and characterize such layers to support electronic cleansing. It is shown that the model sustains robust estimation of the location a...

Objective(s): Determination of stages of colon cancer is done by biopsy usually after surgery. Metabolomics is the study of all the metabolites using LC-MS and 1HNMR spectroscopy with chemometric techniques. The stages of colon cancer were detected from patients' sera using 1HNMR. Materials and Methods: Five ml blood was collected from 16 confirmed patients referred for colonoscopy.  One group ...

background: arteriovenous malformations are one of the most common vascular disorders of the colon. vascular disorders present as painless, high-volume rectal bleeding. case presentation: this study elucidates two rare cases of vascular disorders that are diagnosed as angiodysplasia of the left colon and cavernous hemangioma of the colon and rectum.  the chief complaint in two patients was rect...

Virtual Endoscopy is a technique to explore hollow organs and anatomical cavities using 3D medical imaging and computer graphics. Virtual Endoscopy turns out to be a promising technique to improve, or even in some procedures substitute, real endoscopy. A real endoscopy is invasive and usually implies some risk for the patient. In the last decades, much research has been done in this field. This...

Introduction: Colon adenocarcinoma is one of the foremost causes of cancer mortality. Oral metastasis of colon adenocarcinoma is, however, rare and indicates an end-stage disease process.   Case Report: We report a case of a 69-year-old female with a gingival mass diagnosed with colon adenocarcinoma and liver metastasis after one year. A swelli...