background: caffeine increases the camp production that stimulates spermatozoa movement. caffeine is also used for induction of in vitro acrosome reaction in mammalian spermatozoa, an important step in achieving fertilization. objective: the aim of this study was to assess the effect of caffeine on sperm's motility, vitality and laboratory fertilization rates in mouse in two t6 and m16 media. m...

background:   case: we discuss 3 clinical cases of tubo-ovarian abscess in women with endometriosis after oocyte retrieval despite antibiotic prophylaxis between 2004 and 2011 at our center, and discuss our experience in the context of earlier reports.   conclusion: it is unclear whether antibiotic prophylaxis is necessary in these women, and which antibiotic is best. only douching with povidon...

background: the selection of blastocyst warmed for transfer is based on pre-freeze morphology in vitrified-warmed single blastocyst transfer cycles. but, it is controversial which parameter of blastocyst morphology most closely related to the clinical outcomes. objective: to estimate the effect of blastocoele expansion, trophectoderm (te) morphology grade, and inner cell mass (icm) morphology g...

background: leukemia inhibitory factor (lif) is a 45-56 kda glycoprotein that has an important role in proliferation and embryo implantation. its effect on oocyte maturation and how to exert the function remained to be elucidated. methods: immature mice superovulated with human menopausal gonadotropin and germinal vesicle (gv) oocytes were obtained from ovary 48 hours after. gv oocytes were cul...

vitamin c, an antioxidant substance soluble in water, can react with amino groups of proteins to form schiff bases. as diabetes leads to glycation of various protein which has effect on structure and biochemical activity of them, the inhibition of this process seems very vital. for several years researches in this field have done their best to recognize the antidiabetics compounds. the aim of t...

background and purpose: despite the availability of various treatments for fungal diseases, there are some limitations in the management of these conditions due to multiple treatment-related side-effects. the present study was designed to investigate the antifungal properties of different extracts from pistacia atlantica desf. materials and methods: different parts of p. atlantica (i.e., dried ...

objective(s): the aim of this work was to investigate the effect of the natural and the chemically modified form of cyclodextrins namely; β-cyclodextrin (β-cd) and hydroxypropyl-β-cyclodextrin (hp-β-cd) respectively on the solubility and dissolution rate of aripiprazole; an antipsychotic medication showing poor aqueous solubility.   materials and methods: phase solubility of aripiprazole with t...

background: based on recent studies, there are controversial reports on the ca-pacity of tissue cyst forming of toxoplasma gondii rh strain. in this study, the capac-ity was evaluated by in vivo and in vitro experiments. methods : rh strain was subcutaneously inoculated to ten wistar rats. after one month, their blood, brain, tongue and diaphragm were collected and evaluated by mat, pcr, pathol...

background: echinococcus granulosus , a zoonotic cestode parasite, causative agent of hydatid cyst is endemic in many parts of the world including the middle east. study on different aspects of this parasite is very important and valuable. however, working with adult worms which their habitat situated in the small intestine of canids, is dangerous and risky. achieving such risky situa­tion need...