We compared the effects of DQ-113, a new quinolone, to those of vancomycin (VCM) and teicoplanin (TEIC) in murine models of hematogenous pulmonary infections caused by methicillin-resistant Staphylococcus aureus (MRSA) and VCM-insensitive S. aureus (VISA). The MICs of DQ-113, VCM, and TEIC for MRSA were 0.125, 1.0, and 0.5 microg/ml, respectively; and those for VISA were 0.25, 8.0, and 8.0 micr...

Preproduction and current models of the miniature Wright peak flow meter have been compared with the standard Wright peak flow meter on normal and abnormal subjects. Early problems in production appear to have been overcome, and the current model agrees to within 3% with the standard peak flow meter, which is as close as the agreement between two standard instruments. The new mini-meter may be ...

Multi-DOF motion is realized in the eyes and joints of robots mostly through combination multiple one-degree-of-freedom (1-DOF) motors. However, this results reduced efficiency, a large volume, response speed, inaccurate positioning. To solve these problems, study proposes novel 3-DOF spherical voice coil motor (VCM). In VCM, 16 coils radially oriented ring magnet are used to generate Lorentz f...

This paper presents a novel networking architecture designed for communication intensive parallel applications running on clusters of workstations (COWs) connected by high speed networks. This architecture permits (1) the transfer of selected communication-related functionality from the host machine to the network interface coprocessor, and (2) the exposure of this functionality directly to app...

OBJECTIVE To design an alternative painless method for vancomycin (VCM) monitoring by withdrawing interstitial fluid (ISF) the skin using dissolving microneedles (DMNs) and possibly replace the conventional clinical blood sampling method. METHODS Male Wistar rats were anesthetized with 50 mg/kg sodium pentobarbital. Vancomycin at 5 mg/mL in saline was intravenously administered via the jugula...

Vancomycin hydrochloride (VCM) is a glycopeptides antibiotic. We intend to optimize preparation condition of VCM nanoparticles. Nanoparticles have high bioavailability and oral absorbable fraction. After drug to polymer ratio optimization, loading efficiency, production yield and particle size were measured by changing the organic phase volume, aqueous phase volume and emulsifier concentration ...

A new method for optimum shape design of variable capacitance micromotor VCM using Differential Evolution DE , a stochastic search algorithm, is presented. In this optimization exercise, the objective function aims to maximize torque value and minimize the torque ripple, where the geometric parameters are considered to be the variables. The optimization process is carried out using a combinatio...

Physicians have difficulties to access and analyse information in a medical record. In a previous work on drug databanks, we have shown that with an iconic language as VCM, an icon-based presentation can help physicians to access medical information. Our objective, herein, is to study whether VCM can be used in an electronic medical record for facilitating physician access in general practice. ...

Abstract Vancomycin (VCM) is an antimicrobial that recommended for therapeutic drug monitoring (TDM) maintaining the efficacy and safety of treatment. The trough has been used to guide VCM dosing regimens. However, newer guidelines recommend use area under curve/minimum inhibitory concentration (AUC/MIC)-guided vancomycin dosing, there a need easier more frequent measurements concentrations. Th...

G raham Hutchings of Cardiff University made a discovery in 1982 that came to define his career. He predicted that golddespite its reputation for being inertshould be an excellent catalyst for an industrial reaction that makes vinyl chloride monomer (VCM, or chloroethene), used to produce one of the world’s most ubiquitous plastics, polyvinyl chloride (PVC). More than three decades later, Hut...