www.aafp.org/afp AMERICAN FAMILY PHYSICIAN 1269 involves human papillomavirus (HPV) infection, which leads to VIN and predisposes the patient to vulvar cancer. The second type involves vulvar non-neoplastic epithelial disorders (VNED) and advanced age, leading to cellular atypia and cancer (Table 1). Vulvar cancer most frequently occurs in women 65 to 75 years of age. It can develop in younger ...

Introduction: Poroid hidradenomas (PH) are rare benign skin adnexal tumours with eccrine differentiation. PH have features of both poroma and hidradenoma, wholly intradermal. Few been reported in the literature, here we present two cases localised to left knee. The common histological examination finding was a circumscribed cyst lined by basaloid cells resembling poroma, occasional ductal struc...

Vulvar pruritus is a common symptom in post-menopausal women and treatment is easy if the diagnosis is duly recognized. The purpose of this study is to show the importance of colposcopic examination and directed biopsies in 27 post-menopausal women with pruritus. Biopsy sites were selected by colposcopy. The prevalence of vulvar pruritus, vulvar pathologies, vulvar dystrophies and vulvar intrae...

Vulvar cancer is a rare gynecological malignancy with mainly lymphatic spread. Sentinel node mapping plays an important role in the management of this gynecological malignancy. In the current study, we reported our experience in sentinel node mapping of vulvar cancer and review the literature accordingly. Since the introduction of sentinel node mapping to the surgical oncology community of our ...

synchronous cancer is referred to two or more histological distinct malignancies diagnosed during the same hospital admission. globally more than 1 million people get colorectal cancer yearly resulting in about 0.5 million deaths. vulvar cancer is the fourth most common gynecologic cancer (following the corpus uterine cancer, cancer of ovary and cervix) and comprises only 4 percent of malignanc...

fibroadenoma of the vulva is an uncommon lesion. it has been suggested that they originate from vulvar mammary like other glands. a few examples of benign and malignant vulvar tumors arising from such glands have been reported. a 32-year-old woman was referred with a subcutaneous mass at the vulva. the patient treated by simple excisional surgery with adequate peripheral margin. histological fi...

Primary tuberculosis (TB) of the vulva is very rare. The authors reported here a case of primary ulcerative vulvar TB in a 14 -yearold virgin girl. The diagnosis was based on the pathological finding on tissue biopsy, followed by anti tuberculosis therapy; the vulvar ulcer was completely healed. Vulvar TB must be considered when a persistent vulvar ulcer fails to respond to ordinary treatment.

Cutaneous cylindroma is an adnexal tumour with apocrine differentiation. A predisposition to multiple cylindromas is seen in patients with Brooke-Spiegler syndrome, who carry germline mutations in the tumour suppressor gene CYLD. Previous studies of inherited cylindromas have highlighted the frequent presence of bi-allelic truncating CYLD mutations as a recurrent driver mutation. We have previo...

OBJECTIVE To evaluate the increased value of using coronal reformation of a transverse computed tomography (CT) scan for detecting adnexal torsion. MATERIALS AND METHODS This study included 106 woman suspected of having adnexal torsion who underwent CT with coronal reformations and subsequent surgical exploration. Two readers independently recorded the CT findings, such as the thickening of a...

introduction spinal tumours may be classified in three groups: 1) extradural, 2) intradural extramedullary and 3) intramedullary spinal cord tumours. intradural extramedullary tumours arise from the leptomeninges or nerve roots and include schwannomas. a schwannoma is usually a firm grey-whitish tumour growing near a nerve trunk or ramus. it can be separated from the nerve without damaging neur...