Urinary sodium output increases in the first several days of fasting both in humans and rabbits. The major causal factor of the fasting-induced natriuresis was proposed to be glucagon (1), but the mechanism remains obscure. We have recently observed that fasting for one to four days resulted in the negative sodium balance in rats provided a low salt diet and saline (2). The fasting-induced natr...

Elephant seal weanlings demonstrate rates of endogenous glucose production (EGP) during protracted fasts that are higher than predicted on the basis of mass and time fasting. To determine the nonoxidative and oxidative fate of endogenously synthesized glucose, substrate oxidation, metabolic rate, glycolysis, and EGP were measured in fasting weanlings. Eight weanlings were sampled at 14 days of ...

Materials and methods Male Wistar rats were primary divided into two groups: Control (C) received standard chow and water ad libitum; Fructose (F) received standard chow and water containing 7% of fructose ad libitum. At 90 days of age they were one more time re-divided into 4 groups: Control treated with water (C, n=7); Control treated with HS (CHib, n=6); Fructose treated with water (F, n=8);...

The arcuate nucleus of the hypothalamus (ARH) is involved in the control of energy homeostasis. This is the first study on the ultrastructural response of ARH neurons in aged rats after short-term fasting and subsequent refeeding. Male Wistar rats (24 weeks old) were fasted for 48 or 96 hours and were then refed for 24 hours. The controls were normally fed. The rats received water ad libitum. I...

BACKGROUND Ipragliflozin, a sodium-glucose transporter 2 inhibitor, was administered to patients with type 2 diabetes mellitus for 24 weeks to evaluate its effect on glycemic control and body composition. METHODS This was an investigator-initiated multicenter prospective intervention study in which ipragliflozin (50 mg) was administered once daily and glycemic control, blood pressure, body we...

background: during the ramadan ceremony, adult muslims abstain from drinking and eating between sunrise and sunset. it seems influence on their lifestyle such as eating behavior, meal schedule and also their sleeping. these changes may effect on the endocrine and neuroendocrine circadian patterns and consequently on cardiovascular indices. this study was performed to assess the effects of ramad...

Daily (24 h) rates of water and electrolyte turnover were measured in a conventional balance study in ten adult female pastel mink (Mustela vison) given free access to a standard mink feed for a 1-week conditioning period, followed by a 4 d experimental period and a 2 d fasting period. Drinking water was available throughout. In addition, the completeness of urine collection and the fraction of...

Previous studies suggest that Ramadan exposure during pregnancy might affect the health of women and their babies, particularly through the effect of fasting. This study aimed to evaluate the association between Ramadan exposure and fasting during pregnancy on the birth weight of newborns. This study concerned 1351 pregnant women from a prospective cohort in Jakarta, Indonesia. Ramadan exposure...