Virus-transformed pre-B cells undergo ordered immunoglobulin (Ig) gene rearrangements during culture. We devised a series of highly sensitive polymerase chain reaction assays for Ig gene rearrangement and unrearranged Ig gene segment transcription to study both the possible relationship between these processes in cultured pre-B cells and the role played by heavy (H) chain (mu) protein in regula...

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NF-KB is a nuclear protein, found only in cells that transcribe immunoglobulin light chain genes, that interacts with a defined site in the K immunoglobulin enhancer. This protein can be induced in pre-B cells by stimulation with bacterial l ipopolysaccharlde (LPS). The induction involves a posttranslational activation, and the combined action of LPS and cycloheximide causes a superinduction. A...

Extreme voices are frequently spotted to have a significant effect on public opinions online forums or social media, but very little is known about when, what, and how tone it towards softened manage them. To deal with the large volume of extreme opinions, companies, PR authorities spent heavily soothing tension sheltering customer word-of-mouth from devasting reviews by feeding overloaded info...

Existing text based CAPTCHAs can only transcribe words in an image that contains ASCII characters. In this paper, we are describing a system called UCAPTCHA, which is intended to transcribe words in an image that contains Unicode characters to text. Such a system will be useful in transcribing scanned documents from many European languages like Spanish, German, French etc.

The publication of Vannevar Bush’s seminal paper, As we may think, in 1945 was closely followed by the invention of the electronic digital computer in 1948. In the following 50 years much of Bush’s vision has been realised by computer scientists. We can store vast amounts of data including speech and video in computers, and we can transmit them over networks. We can annotate the material with e...