BACKGROUND Different doses of contrast agent are applied for magnetic resonance perfusion studies and mainly semiquantitative approaches have been reported for analysis. We aimed to determine the optimal dose for a visual detection of perfusion defects. METHODS 49 patients (59+/-8 years; 33 male) scheduled for invasive angiography were examined at stress (0.14 mg adenosine/kg body weight/minu...

BACKGROUND The aim of this study was to present and compare the results of proposed methods for optimal red cell mass and plasma volume (RCM&PV) estimation, and their influence on the interpretation of obtained results. MATERIAL AND METHODS In 120/280 patients with polycythaemia rubra vera, subjected to RCM&PV determination with autologous erythrocytes in vitro labelled with 51Cr-sodium chrom...

A 62-year-old woman presented to a hospital in rural Australia with complaints of left lower quadrant abdominal pain, bloating, dyspnea, and a dry cough. She reported weight loss of 4 kg over 2months (previously, 48.5kg), fevers, and fatigue. Her medical history was significant for chronic constipation since age 20 years, and hemorrhoidectomy at age 59 years. Physical examination revealed moder...

A study involving 825 spring ewe lambs was conducted to evaluate effects of breed, heterosis, type of birth and rearing, age of dam and preweaning and postweaning growth rate on occurrence of puberty before November 10. Within a breed or breed-cross, preweaning competition among twin and triplet lambs reduced lamb weights by 4 or 5 kg at 70 (weaning), 160 and 230 days of age and by about 3 kg a...

Milk samples averaging 500 ml were collected weekly from 10 to 54 days postpartum from five lactating mares. Samples were obtained by hand milking after oxytocin administration and while the foal nursed. Dry matter, protein and gross energy were higher in samples obtained at 10 and 17 days postpartum than those obtained during the midlactation period of 24-54 days. Midlactation samples averaged...

BACKGROUND AND PURPOSE It is unknown whether a combination of vasopressin and epinephrine may be superior to vasopressin alone by targeting both nonadrenergic and adrenergic receptors. METHODS After 15 minutes of cardiac arrest (13 minutes of ventricular fibrillation and 2 minutes of pulseless electrical activity) and 3 minutes of chest compressions, 16 animals were randomly treated with eith...

The choice of injected dose of 18 F -FDG and acquisition time is important in obtaining consistently high-quality PET images. The aim of this study was to determine the optimal acquisition protocols based on patient weight for 3-dimensional lutetium oxyorthosilicate PET/CT. Methods: This study was a retrospective analysis of 76 patients ranging from 29 to101 kg who were injected with 228–395.2 ...

PURPOSE High-intensity interval training (HIIT) is documented to yield effective improvements in the cardiovascular system and be an excellent strategy for healthy aging. However, it is not determined how age may affect the training response of key components of aerobic endurance. METHODS We recruited 72 males (mean ± SD, weight = 84.9 ± 12.9 kg, height = 180.4 ± 5.8 cm) and 22 females (weigh...

In a prospective cohort study, associations of resting heart rate with risk of coronary, cardiovascular disease, cancer, and all-cause mortality in age-specific cohorts of black and white men and women were examined over 22 years of follow-up. Participants were employees from 84 companies and organizations in the Chicago, Illinois, area who volunteered for a screening examination. Participants ...

BACKGROUND Elevated uric acid (UA) is associated with the presence of the metabolic syndrome (MetS). In a prospective cohort study, we assessed whether baseline and longitudinal change in UA were risk factors for development of MetS and its individual components. METHODS We included 3087 women and 2996 men who had UA measured in the population based Tromsø Study 1994-95. The participants were...