Highly effective anthracyclines, like doxorubicin (DOX), have limited clinical use due to protracted cardiotoxic effects. While exercise is known to be cardioprotective, it is unclear whether exercise compromises chemotherapy treatment efficacy. To determine the effect of exercise training on DOX antitumor efficacy as well as DOX-induced cardiotoxicity, female Fisher 344 rats were randomly assi...

The light spectrum plays a major role in regulating plant growth and development, influencing photosynthesis photo-morphogenesis. objective was to evaluate the weight antioxidant activity of ‘Lavinia’ lettuce (Lactuca sativa L. var. capitata L.) plants under LED lights with different red:blue ratios (R:B) used as supplement ambient greenhouse at seasons. Five supplemented treatments were us...

The kinematic structure of a sample of planetary nebulae, consisting of 23 [WR] central stars, 21 weak emission line stars (wels) and 57 non-emission line central stars, is studied. The [WR] stars are shown to be surrounded by turbulent nebulae, a characteristic shared by some wels but almost completely absent from the non-emission line stars. The fraction of objects showing turbulence for non-...

Studies of V79-171 cells were undertaken to determine what extracel lular or intracellular derivative of the drug WR-2721 is associated with radioprotection. The effect of preincubation at 23 ±1°Cwith WR-2721, and with derivatives of WR-2721 produced in medium containing alkaline phosphatase, upon survival of cells following subsequent -y-irradiation was examined. It was established that WR-2...

Six parent diallel cross without reciprocal was studied to investigate the genetic behavior of different agronomic traits in rice. The analysis of Wr-Vr graph showed that panicle length, thousand grain weight and grain yield per plant did not follow the additivedominance model indicating epistatic gene action responsible for the expression of these traits. All other traits under the study were ...

Previously, we have reported the synthesis of a homochiral l-cyclic peptide [WR]5 and its use for delivery of anti-HIV drugs and biomolecules. A physical mixture of HAuCl4 and the peptide generated peptide-capped gold nanoparticles. Here, [WR]5 and [WR]5-AuNPs were tested for their efficiency to deliver a small interfering RNA molecule (siRNA) in human cervix adenocarcinoma (HeLa) cells. Flow c...

Context. The favoured progenitors of long-duration gamma-ray bursts (GRBs) are rapidly rotating Wolf-Rayet (WR) stars. However, most Galactic WR stars are slow rotators, as stellar winds are thought to remove angular momentum. This poses a serious challenge to the collapsar model. Recent observations indicate that GRBs occur predominately in low metallicity (Z) environments, which may resolve t...