here we report a novel approach for preparation of a 6-day transdermal drug delivery system (tdds) as treatment for mild to moderate alzheimer’s disease. the spray drying method was used to prepare microparticles containing the anti-alzheimer drug. the content of the drug was determined by high performance liquid chromatography (hplc) method. the morphology and size range of the microparticles ...

We address a single-machine scheduling problem where the objective is to minimize the weighted mean absolute deviation of job completion times from their weighted mean. This problem and its precursors aim to achieve the maximum admissible level of service equity. It has been shown earlier that the unweighted version of this problem is NP-hard in the ordinary sense. For that version, a pseudo-po...

Despite the popularity and empirical success of patch-based nearest-neighbor and weighted majority voting approaches to medical image segmentation, there has been no theoretical development on when, why, and how well these nonparametric methods work. We bridge this gap by providing a theoretical performance guarantee for nearest-neighbor and weighted majority voting segmentation under a new pro...