From 2003 to 2013, 55 patients (median age 3.3 years; 29 males, 26 females) with unresectable, metastatic, or diffuse anaplastic histology (AH) Wilms tumor were treated with neoadjuvant transcatheter arterial chemoembolization (TACE) and systemic chemotherapy. Characteristics In: Wilms Tumor. Marry M. van den Heuvel-Eibrink (Editor) ISBN: 978-0-9944381-1-9; Doi: http://dx.doi.org/10.15586/codon...

Wilms’ tumor (nephroblastoma) is a malignant renal tumor that arises from abnormal proliferation of metanephric blastema without differentiation into glomeruli and tubules. It is the most common malignant kidney tumor in children and accounts for 6% of all childhood malignancies. Nephroblastoma is a very rare tumor in the adult age group. Only 3% off all Wilms’ tumors are diagnosed in age over ...

BACKGROUND Although the NWTSG and SIOP studies have included the largest number of patients, several individual institutions have made likewise important contributions to the optimization of Wilms' tumor therapy. The purpose of this study is to present our personal experience obtained in the last 42 years by treating Wilms' tumor in childhood. PATIENTS AND METHODS Throughout the period 1965-2...

PURPOSE A number of studies have indicated that the tumor proliferation marker MIB-1 and cell cycle inhibitor p27(Kip1) expression are of prognostic importance in a variety of cancers. The present study was performed to evaluate the prognostic value of these molecules in Wilms' tumors. EXPERIMENTAL DESIGN MIB-1 and p27(Kip1) expressions were investigated by the means of immunohistochemical an...