There are two major pathways for repairing DNA double strand breaks in mammalian cells: nonhomologous end joining (NHEJ) and homologous recombination repair (HRR). The nonhomologous end joining repair is deficient in cells without Ku, whereas HRR is highly efficient in such cells compared with their wild-type counterparts. The mechanism remains unclear. We reported previously that Ku80(-/-) cel...

Coulomb effects in granular materials at not very low temperatures. Abstract We consider effects of Coulomb interaction in a granular normal metal at not very low temperatures suppressing weak localization effects. In this limit calculations with the initial electron Hamiltonian are reduced to integrations over a phase variable with an effective action, which can be considered as a bosonization...

Article history: Received 13 March 2014 Received in revised form 4 June 2014 Accepted 14 July 2014 Available online xxxx General intelligence has been shown to exist within and among species of mammals and birds. An important question concerns whether it is the principal source of differences in cognitive abilities between species, as is the case with comparisons involving many human population...

The effects of C by N replacement on the intramolecular hydrogen bond of malonaldehyde have been analyzed through the use of B3LYP/6-311++G(3df,2p)//B3LYP/6-311+G(d,p) calculations. Formylformimidic acid (1) exhibits a IMHB much stronger than that of malonaldehyde, reflecting the enhancement of both the intrinsic acidity and basicity of the HB donor and HB acceptor, when C is replaced by nitrog...

CONTEXT Controversy and uncertainty ensue when the results of clinical research on the effectiveness of interventions are subsequently contradicted. Controversies are most prominent when high-impact research is involved. OBJECTIVES To understand how frequently highly cited studies are contradicted or find effects that are stronger than in other similar studies and to discern whether specific ...

The flavonoid rutin is recognized as playing an important role in the protection of plants against lepidopterans. Bioassays with this compound are generally carried out using artificial diets. Proteins of high energy value, such as casein, are important ingredients of insect artificial diets as a source of essential amino acids. However, such proteins can generally increase the allelochemical a...

A gauge model with chiral color symmetry is considered and possible effects of the color G-boson octet predicted by this symmetry are investigated in dependence on two free parameters, the mixing angle θG and G ′ mass mG′ . The allowed region in the mG′ − θG plane is found from the Tevatron data on the cross section σtt̄ and forward-backward asymmetry A pp̄ FB of the tt̄ production. The mass limit...