An in vitro study on the role of intracellular calcium ions in healing of excisional wound in rabbit was undertaken. We employed two drugs namely, glibenclamide and nitroglycerin that are topically applied in vivo to modulate the activity of intracellular calcium. Our model consisted of a 15 ´ 15 mm excisional wound. Seven groups of New Zealand rabbits were used. The first three groups served a...

a 21-year-old woman presented with a painless growing mass in her right flank since 5 months before. with the probable diagnosis of a cold abscess, the patient was operated, but the wound was not cured. the patient was re-examined and a biopsy from the lesion was taken which revealed hydatid cyst. after nearly complete excision of the infected area and adjuvant chemotherapy with albendazole for...

The stem bark of Carallia brachiata was studied for wound healing activity. The bark was extracted with petroleum ether, ethyl acetate and methanol successively. All the extracts were screened for wound healing activity by excision and incision models in Wistar rats. The ethyl acetate and methanol extracts were found to possess significant wound healing activity. The extracts revealed the prese...

Reconstruction of left groin defect following a failed left femoral aneurysm bypass procedure. The defect was occasioned by excision of a saccular aneurysm of left femoral artery, and repair with PTFE graft for an ilio femoral bypass. On the second postoperative day, the wound became septic and the graft extruded with a resultant wound defect of about 20 x 10 cm. The graft was later removed and...

OBJECTIVE To present the technique of and indications for serial excision of facial hemangiomas. METHODS Clinical review of patients cared for by the senior author (M.H.) in a private-practice specialty center. RESULTS Forty-six patients underwent serial excision of facial infantile hemangiomas. The average number of excisions was 3 (range, 2-5), with a mean interoperative period of 4 month...

Full-thickness burns around the knee joint are usually associated with exposure of bone, tendon or ligaments. Following excision of the deep burns, there is no viable wound bed to which skin grafts can be applied. Although vacuum-assisted closure has been used to encourage granulation tissue, exposure of the tendons and ligaments following excision usually requires muscle flaps or fasciocutaneo...

BACKGROUND Significant blood loss continues to plague early tangential excision of the burn wound. Although various techniques to reduce intraoperative blood loss have been described, there is an absence of uniformity and consistency in their application. Furthermore, it is unclear whether these techniques compromise intraoperative tissue assessment and wound outcome. The purpose of this study ...

BACKGROUND Malignant proliferating trichilemmal tumor (MPTT) is a rare neoplasm originating in the outer sheath of a hair follicle that often presents as a slowly enlarging, painful, subcutaneous scalp nodule. The authors describe a case of malignant proliferating trichilemmal tumor (MPTT) in an elderly 65-year-old Asian male who presented with a 5.5 x 5.0 cm mass on the posterior scalp. METH...

The main objective of this study was to evaluate the wound healing activity of Tribulus Terrestris Linn. (TT) fruits in swiss albino rats. The fruit body of Tribulus Terrestris rich in tannins and phenolic content. Dried fruits of Tribulus Terrestris powder were used for ointment preparation. Healthy adult swiss albino rats (18-22)g were subjected to acute toxicity studies as per OECD guideline...

The healing potential of ethanolic extract of aerial parts of Sphaeranthus amaranthoides, Linn. (Asteraceae) (SAE) for treatment of dermal wounds in wistar rats was studied on excision wound models. Various parameters studied are epithelization and wound contraction. The extract was applied in thedorsal thoracic region of six excised wounded models once in a day for 16 days. The results obtaine...