Within the frame of upgrading and modernisation Water Supply System (WSS), our work is focussing on safety systems/devices implemented or that should be in WSS. The implementation systems supposed to reduce hazard occurrence hazardous consequences case a WSS unsafe disruption. To assess this reduction, we preconise use integrity levels standards. undertaken ground multi-barriers safeguard appro...

background: aneurysm is a blood-filled bulge in the wall of vessels that occurred in abdominal aortic and cerebral vessels. the dilation of artery leads to aneurysm. methods: three dimensional modelling was utilized for a patient with cerebral aneurysm and a normal subject, and additional fluid-structural interaction simulation was performed. we consider pulsatile blood velocity as inlet, and b...

Background Beta-blockers are the recommended medical treatment for slowing ascending aorta (AAo) dilation in patients with bicuspid aortic valve (BAV). Wall shear stress (WSS) has been shown to promote endothelial cell dysfunction [1] and AAo WSS may play a role in aortic aneurysm growth. Time-resolved 3D phase contrast (4D flow) MRI allows for the quantification of 3D WSS regionally in the tho...

Due to the availability of huge number of Web services (WSs), finding an appropriate WS according to the requirement of a service consumer is still a challenge. In this paper, we present a new and flexible approach, called SeqDisc, that assesses the similarity between WSs. In particular, the approach exploits the Prüfer encoding method to represent WSs as sequences capturing both semantic and s...

This paper presents a numerical study of the behaviour of wall shear stress (WSS) in three-dimensional pulsatile flow through an axisymmetric stenosed artery. A realistic blood flow rate (250 ml min−1 at rest in coronary artery [7]) and cardiac cycle (T=0.84s [5]) are applied in the simulations. The flow is fully three-dimensional, and the fluid is assumed to be Newtonian and incompressible. Di...

The spatial and temporal distributions of wall shear stress (WSS) in prototype vessel geometries of coronary segments are investigated via numerical simulation, and the potential association with vascular disease and specifically atherosclerosis and plaque rupture is discussed. In particular, simulation results of WSS spatio-temporal distributions are presented for pulsatile, non-Newtonian bloo...

PURPOSE Coronary artery bypass graft (CABG) surgery represents the standard treatment of advanced coronary artery disease. Two major types of anastomosis exist to connect the graft to the coronary artery, i.e., by using an end-to-side or a side-to-side anastomosis. There is still controversy because of the differences in the patency rates of the two types of anastomosis. The purpose of this pap...

BACKGROUND We hypothesized that nebivolol, a β-blocker with nitric oxide-mediated activity, compared with atenolol, a β-blocker without such activity, would decrease oxidative stress and improve the effects of endothelial dysfunction and wall shear stress (WSS), thereby reducing atherosclerosis progression and vulnerability in patients with nonobstructive coronary artery disease. METHODS AND ...

BACKGROUND Low wall shear stress (WSS) increases neointimal hyperplasia (NH) in vein grafts and stents. We studied the causal relationship between WSS and NH formation in stents by locally increasing WSS with a flow divider (Anti-Restenotic Diffuser, Endoart SA) placed in the center of the stent. METHODS AND RESULTS In 9 rabbits fed a high-cholesterol diet for 2 months to induce endothelial d...