True isochromosomes for Xp probably do not exist in a liveborn. We describe a rare case of complete Xp duplication and retention of the inactivation centre at Xq13. Cytogenetically, it is described as a nonmosaic 46,X,psu idic(X)(q13). Complete duplication of Xpter-->Xq13 was confirmed by banded analysis and FISH probes for X centromere, Xp21, XIST locus, and whole chromosome paints for X and Y...

Extreme Programming (XP) is a well known agile software development methodology which is ideal for projects featured as highly unpredictable in tasks with limited resources. The continuous discussion on the usage and importance of each XP practice lead us to explore what are the most important XP practices to be applied in certain projects. This study examined the actual usage amount and percei...

Genetic alterations affecting nucleotide excision repair, the most versatile DNA-repair mechanism responsible for removal of bulky DNA adducts including ultraviolet (UV) light-induced DNA lesions, may result in the rare, recessively inherited autosomal syndromes xeroderma pigmentosum (XP), Cockayne syndrome (CS), or trichothiodystrophy (TTD). Classical approaches such as somatic cell fusions or...

Attaining consensus among the success-critical stakeholders is crucial for the success of any software engineering project. Extreme Programming (XP) addresses this fact by providing a set of negotiation-oriented practices. In this paper we discuss negotiation techniques that would nicely complement XP. We present the EasyWinWin requirements negotiation approach and discuss its potential benefit...

The prevalence of systems development project failures has been well documented. eXtreme Programming (XP) is a software development methodology that seeks to eliminate many of the shortcomings of cumbersome life cycle oriented traditional methodologies. We explore some of the basic tenets of XP and Agile methodologies and present the thoughts of two of the proponents and early participants in t...

eXtreme Programming (XP) ist eine Symbiose verschiedener Techniken, die erst durch ihr Zusammenwirken ihre besondere Qualität agiler Softwareentwicklung aufweisen. Sie lassen sich theoretisch leicht vermitteln – ihr Wert erschliesst sich aber nur durch eigene Praxis. Soll XP im Rahmen universitärer Lehre adäquat vermittelt werden, müssen die Anforderungen industrieller Praxis in geeigneter Weis...

One of the pivotal roles in XP is the customer, but little guidance is provided in the literature on the practicalities of succeeding in this role. We used an interpretative in-depth case study to explore a successful XP project. We obtained multiple perspectives on the implementation of the customer role, and this paper includes excerpts from interviews with the customer and other development ...

Extreme programming (XP) is arguably improving the productivity of small, co-located software development teams. In this extended abstract, we describe an approach that overcomes the XP constraint of co-location by introducing a process-support environment (called MILOS) that helps software development teams to maintain XP practices in a distributed setting. MILOS supports project coordination,...

This paper describes the incremental adoption of XP (extreme programming) practices. The relationship of XP to previous work in usability engineering is described. The centrality of user stories is emphasized and illustrated with anecdotes from the development of systems traditionally and with XP.

Extreme programming (XP) is arguably improving the productivity of small, co-located software development teams. In this paper, we described an approach that overcomes the XP constraint of colocation by introducing a process-support environment (called MILOS) that helps software development teams to maintain XP practices in a distributed setting. MILOS supports project coordination, information...