نتایج جستجو برای: xx male
تعداد نتایج: 339463 فیلتر نتایج به سال:
BACKGROUND Disorders of sex development (DSD) is a group of sexual differentiation disorders resulting in genital anomalies with defects in gonadal hormone synthesis and/or incomplete genital development. These conditions result in problems concerning the sex assignment of the child. This study aims to describe the clinical features, diagnosis and management of children with DSD in southern Tha...
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Background and aims: <span style="color: #221e1f; font-family: Optima ...
Background and aims: <span style="color: #221e1f; font-family: Optima ...
Sex reversal in males with female karyotypes is likely to be caused by the presence of cytogenetically undetectable Y-chromosomal DNA sequences that include the testis-determining gene(s). Studying a total of sixteen 46,XX males and one 47,XXX male, we detected Y-chromosomal DNA in 13 of the XX males (i.e. 80%) and in the 47,XXX male. The amount of Y-chromosomal DNA present in the patients vari...
Sex in mammals is genetically determined and is defined at the cellular level by sex chromosome complement (XY males and XX females). The Y chromosome-linked gene sex-determining region Y (SRY) is believed to be the master initiator of male sex determination in almost all eutherian and metatherian mammals, functioning to upregulate expression of its direct target gene Sry-related HMG box-contai...
BACKGROUND Drosophila melanogaster females have two X chromosomes and two autosome sets (XX;AA), while males have a single X chromosome and two autosome sets (X;AA). Drosophila male somatic cells compensate for a single copy of the X chromosome by deploying male-specific-lethal (MSL) complexes that increase transcription from the X chromosome. Male germ cells lack MSL complexes, indicating that...
Background: Division of Human Genetics (DHG) is a referral center for karyotyping and counseling to the couples as well as to the individuals referred with bad obstetric history and infertility. Materials and Methods: From 1972 to 2003, overall 1666 couples and 131 female partners with bad obstetric history (BOH) such as; spontaneous abortions, live births with congenital malformations and stil...
Sex determination in flies relies on the different ratio of X chromosomes to autosomes in XX females and XY males. Mammals have a male-determining Y-linked gene, but may retain dosage-related elements.
The purpose of the present study was to trace the fate of primordial germ cells in mouse chimeras of XX/XY constitution. In this type of research one hopes to obtain knowledge of the role of intrinsic genetic factors and of environmental factors (the environment provided by the gonads) in initiating and directing the course of gametogenesis in mammals. Data obtained up to the present show that ...
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