نتایج جستجو برای: zafirlukast
تعداد نتایج: 158 فیلتر نتایج به سال:
1. Faul JL, Leonard CT, Burke CM, Tormey VJ, Poulter LW. Fluticasone propionate induced alterations to lung function and the immunopathology of asthma over time. Thorax 1998; 53: 753±761. 2. Barnes PJ, Pedersen S. Efficacy and safety of inhaled corticosteroids in asthma. Am Rev Respir Dis 1993; 148: Suppl. 4, S1±S26. 3. Faul JL, Tormey W, Tormey V, Burke CM. High dose inhaled corticosteroids an...
Classical Hodgkin lymphoma (cHL) is characterized histologically by a minority of malignant Hodgkin Reed-Sternberg cells surrounded by abundant inflammatory cells, generally believed to be of major importance in the pathophysiology of the disease. Here, we present data that link inflammatory cell-derived arachidonic acid metabolites, the cysteinyl leukotrienes (CysLT), to the pathogenesis of cH...
The cysteinyl leukotrienes (CysLTs) are potent biological mediators in the pathophysiology of inflammatory diseases, in particular of airway obstruction in asthma. Pharmacological studies have suggested the existence of at least two types of CysLT receptors, designated CysLT(1) and CysLT(2). The CysLT(1) receptor has been cloned recently. Here we report the molecular cloning, expression, locali...
In vitro and in vivo clinical and experimental data have suggested that leukotrienes play a key role in inflammatory reactions of the skin. Antileukotriene drugs, ie, leukotriene receptor antagonists and synthesis inhibitors, are a class of anti-inflammatory drugs that have shown clinical efficacy in the management of asthma and in rhinitis with asthma. We searched MEDLINE database and carried ...
Antileukotriene drugs are new therapeutic agents that have recently been approved for the treatment of asthma. Several cases of eosinophilic conditions including Churg-Strauss syndrome have been reported to be associated with zafirlukast, a cysteinyl leukotriene type 1 receptor antagonist. So far no other leukotriene modifier has been associated with the syndrome. The case history is presented ...
Honeybee stings are a severe public health problem. Bee venom contains a series of active components, including enzymes, peptides, and biogenic amines. The local reactions observed after envenoming include a typical inflammatory response and pain. Honeybee venom contains some well-known polycationic peptides, such as Melittin, Apamin, MCD peptide, Cardiopep, and Tertiapin. Secapin in honeybee v...
Actions of antiallergic drugs depend on their ability to inhibit a particular stage of allergic reaction and to control symptoms of allergic inflammation. Drugs effective in early stage of allergic reaction prevent allergic cascade by acting on dendritic cells, by means of DNA-based therapies resulting both in down-regulation of T-helper cell type 2 (Th2) cytokine profile release and immunoglob...
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