As part of the research efforts to identify plant species which may have potential against tuberculosis, a study was earlier conducted in collaboration with the institute for TB Research, university of illinois, Chicago, to randomly screen the crude alcoholic extracts of different plant species using the MABA assay, to determine any inhibitory activity against the causative agent, Mycobacterium...

The present study investigates the amelioration of diabetic retinopathy (DR) by Zingiber zerumbet rhizome ethanol extracts (ZZRext) in streptozotocin-induced diabetic rats (STZ-diabetic rats). ZZRext contains high phenolic and flavonoid contents. STZ-diabetic rats were treated orally with ZZRext (200, 300 mg/kg per day) for three months. Blood-retinal barrier (BRB) breakdown and increased vascu...

Several metals in soil affect the production of secondary metabolites medicinal plants. In this study, we have determined concentrations K, Mn, Fe, Zn, Cu soils collected at Tinh Bien, Tri Ton, Thoai Son, and Cam Mountain areas An Giang province by X-Ray Fluorescence Spectroscopy (XRF). We simultaneously evaluated total phenolic flavonoid content methanol extracts from Solanum torvum (Sw.) leav...

Sebagai upaya preventif terhadap Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV 2) maka sangat penting bagi masyarakat untuk meningkatkan imunitas tubuh secara mandiri. Berbagai tanaman asli Indonesia telah direkomendasikan oleh BPOM sebagai obat peningkatan di masa pandemi, diantaranya adalah empon-empon. Tujuan systematic review ini membuat kesimpulan ilmiah dari empon-empon imunom...

Zerumbone (ZER), a potential anticancer compound, isolated from the fresh rhizomes of Zingiber zerumbet. In this investigation, the cytotoxic properties of ZER were evaluated, on cancer cells of human cervix (HeLa), breast and ovary, and normal cells of Chinese Hamster ovary, using MTT assay. Apoptogenic effects of ZER on HeLa were studied using fluorescence microscopy (AO/PI double staining), ...

Diabetic retinopathy (DR), the most ordinary and specific microvascular complication of diabetes, is a disease of the retina. Zerumbone (ZER) is a monocyclic sesquiterpene compound, and based on reports, it is the predominant bioactive compound from the rhizomes of Zingiber zerumbet. The aim of the current study is to evaluate the protective effect of zerumbone against DR in streptozotocin (STZ...

Leishmania mexicana is one of the pathogens causing cutaneous leishmaniasis which is associated with patient morbidity. In our researches for new safe and effective treatments, thirty-seven essential oils (EOs) extracted from Vietnamese plants were screened in vitro for the first time on Leishmania mexicana mexicana(Lmm) promastigotes at the maximum concentration of 50 nL/mL. Active EOs were al...