BACKGROUND The molecular defects resulting in a β-thalassemia phenotype, in the Egyptian population, show a clear heterogenic mutations pattern. PCR-based techniques, including direct DNA sequencing are effective on the molecular detection and characterization of these mutations. The molecular characterization of β-thalassemia is necessary for carrier screening, genetic counseling, and to offer...

INTRODUCTION β-Thalassemia and hemoglobinopathies are common genetic disorders in Turkey and in this retrospective study our aim was to determine the frequency of β-thalassemia and hemoglobinopathies in Adana, which is one of the biggest cities located in the southern part of Turkey. MATERIAL AND METHODS Data from 3000 individuals admitted to Seyhan Hereditary Blood Disorders Center in Adana ...

BACKGROUND Takotsubo cardiomyopathy is an acute heart failure syndrome characterized by myocardial hypocontractility from the mid left ventricle to the apex. It is precipitated by extreme stress and can be triggered by intravenous catecholamine administration, particularly epinephrine. Despite its grave presentation, Takotsubo cardiomyopathy is rapidly reversible, with generally good prognosis....

If G is a triangle-free graph, then two Gallai identities can be written as α(G)+ χ(L(G)) = |V (G)| = α(L(G))+ χ(G), where α and χ denote the stability number and the clique-partition number, and L(G) is the line graph of G. We show that, surprisingly, both equalities can be preserved for any graph G by deleting the edges of the line graph corresponding to simplicial pairs of adjacent arcs, acc...

Several regulatory bodies have approved a health claim on the cholesterol-lowering effects of oat β-glucan at levels of 3·0 g/d. The present study aimed to test whether 1·5 g/d β-glucan provided as ready-to-eat oat flakes was as effective in lowering cholesterol as 3·0 g/d from oats porridge. A 6-week randomised controlled trial was conducted in eighty-seven mildly hypercholesterolaemic ( ≥ 5 m...

Global existence and boundedness of classical solutions the chemotaxis–consumption systemnt=Δn−∇⋅(n∇c),0=Δc−nc, under no-flux boundary conditions for n Robin-type conditions∂νc=(γ−c)g c (with γ>0 C1+β(∂Ω)∋g>0 some β∈(0,1)) are established in bounded domains Ω⊂RN, N≥1. Under a smallness condition on γ, moreover, we show convergence to stationary solution.

Let G be a graph of order n. For every v ∈ V (G), let EG(v) denote the set of all edges incident with v. A signed k-submatching of G is a function f : E(G) −→ {−1, 1}, satisfying f(EG(v)) ≤ 1 for at least k vertices, where f(S) = ∑ e∈S f(e), for each S ⊆ E(G). The maximum of the value of f(E(G)), taken over all signed k-submatching f of G, is called the signed k-submatching number and is denote...

under homogeneous Neumann boundary conditions in a bounded domain Ω⊂ℝ n (n≥2). The diffusion function D(s)∈C 2 ([0,∞)) and the chemotactic sensitivity S(s)∈C are given by D(s)≥C d (1+s) -α 00 α,β∈ℝ. nonlinear signal secretion g(s)∈C 1 is supposed to satisfy g(s)≤C g γ foralls≥0 ,γ>0. Global boundedness of solution established specific conditions:

Background: The double heterozygous state of α/β thalassemia may alter the hematological indices and modify the phonotype. In addion, definite characterizaon of co-inheritance of α- and β-thalassemia heterozygous carriers may change the process of genec counseling. Materials and Methods: An Iranian couple with low hematological indices was analyzed for α-globin gene deleons using mulpl...

background : β-thalassemia trait is one of the most common genetic disorders in mediterranean countries. previous studies have shown that β- thalassemia trait has a protective effect against malaria, coronary artery disease, hypertension and alzheimer disease. we hypothesize that due to the shorter life span of red blood cells and increased hematopoiesis, these patients are at increased risk of...