Our understanding of keratoconjunctivitis sicca (KCS), also known as dry eye syndrome, has been changed over recent years. Until lately, the condition was thought to be merely due to aqueous tear insufficiency. Today, it is understood that KCS is a multifactorial disorder due to inflammation of the ocular surface and lacrimal gland, neurotrophic deficiency and meibomian gland dysfunction. This ...

At the interface of animal and world, neurons transform environmental stimuli into spikes of electrical current known as action potentials. As sensory information makes its way from point to point along neural pathways, the numbers of neurons participating in the response and the numbers of spikes they generate often dramatically decrease—that is, the sensory representation becomes sparse (Barl...

Kupffer cells (KCs), the vast pool of intravascular macrophages in the liver, help to clear blood-borne pathogens. The mechanisms by which KCs capture circulating pathogens remain unknown. Here we use intra-vital imaging of mice infected with Staphylococcus aureus to directly visualize the dynamic process of bacterial capture in the liver. Circulating S. aureus were captured by KCs in a manner ...

Abstract Isomorphism detection is fundamental to the synthesis and innovative design of kinematic chains (KCs). The can be performed accurately by using similarity KCs. However, there are very few works on isomorphism based properties similar vertices. In this paper, an ameliorated multi-order adjacent vertex assignment sequence (AMAVS) method proposed seek out vertices identify planar First, s...

Odors evoke complex responses in locust antennal lobe projection neurons (PNs)-the mitral cell analogs. These patterns evolve over hundreds of milliseconds and contain information about odor identity and concentration. In nature, animals often encounter many odorants in short temporal succession. We explored the effects of such conditions by presenting two different odors with variable interven...

Pull control systems are a good way to control material flow in manufacturing systems. In this paper we are interested in four control mechanisms: the Base Stock Control System (BSCS), the Kanban Control System (KCS), the Generalized Kanban Control System (GKCS) and the Extended Kanban Control System (EKCS). The BSCS and the KCS are well known simple pull control mechanisms. The better performi...

Hepatocellular carcinoma (HCC), the most common liver cancer, occurs mainly in men. Similar gender disparity is seen in mice given a chemical carcinogen, diethylnitrosamine (DEN). DEN administration caused greater increases in serum interleukin-6 (IL-6) concentration in males than it did in females. Furthermore, ablation of IL-6 abolished the gender differences in hepatocarcinogenesis in mice. ...

The study was conducted on 18 mixed-breed dogs, aged 2.5 to 10 years. All patients were diagnosed with immunemediated keratoconjunctivitis sicca (KCS) during an ophthalmological examination. A total of 33 corneas and conjunctivae were affected by the disease. Based on the results of Schirmer’s test (STT), the patients were divided into three equal groups. In group I, the STT score was within th...

PURPOSE To use in vivo spectral-domain optical coherence tomography (SD-OCT) to measure corneal, limbal, and bulbar conjunctival epithelial thickness. METHODS A total of 156 eyes of 79 subjects were enrolled in four groups: young control (YC group), < 40 years; middle-aged control (MAC group), > 40 years; patients with dry eye syndrome (KCS group); and patients with glaucoma or ocular hyperte...

This study investigates the effect of soothing liver and invigorating spleen recipes on steatohepatitis examining the IKKβ-NF-κB signaling pathway in KCs of NASH rats. SD male rats were randomly divided into 8 groups, and the NASH model was induced by a high-fat diet (HFD). After 26 weeks, liver tissue was examined in H&E stained sections and liver function was monitored biochemically. KCs were...