Capillary electrokinetic separation techniques offer high efficiency and peak capacity, and can be very useful for the analysis of samples containing a large variety of (unknown) compounds. Such samples are frequently met in impurity profiling of drugs (detection of potential impurities in a pharmaceutical substance or product) and in general sample profiling (determination of differences or si...

The mechanisms by which electrokinetic factors might influence the filtration rate of aqueous electrolyte solutions through membranes are discussed. The filtration rate of a thorium chloride solution in which the membrane is isoelectric is compared with those of other solutions. The maximum filtration rate is found at the isoelectric concentration, the rate falling as the electrokinetic potenti...

Electrokinetic techniques continue to play a leading role in technologies ranging from nanoparticle characterization and directed electronics assembly to micropumps and micromixers to biosensors and DNA sequencing. In this session, we invite submissions related to the development of new technologies in any of these areas, from both the fundamental and applied perspectives. Suitable topics inclu...

We develop a multiphysics model to study the contribution of electrokinetics on the biomolecular detection process and provide a physical explanation of the two to three orders of magnitude difference in detection time between experimental results and theoretical predications at ultralow concentration. The electrokinetic effects, including electrophoretic force and electroosmotic flow, have bee...

Testing is a crucial part of any software project. Its importance can be seen in the increasing amount of developer striving towards producing code with higher testability, thus being able to verify and validate the functionality of their systems. The design and structure of the code is thereby very important, to incorporate testability at a satisfying level. Dependency-Injection(DI) is a way o...

Active manipulation of cells, such as trapping, focusing, and isolation, is essential for various bioanalytical applications. Herein, we report a hybrid electrokinetic technique for manipulating mammalian cells in physiological fluids. This technique applies a combination of negative dielectrophoretic force and hydrodynamic drag force induced by electrohydrodynamics, which is effective in condu...

A field-amplified sample stacking and capillary electrophoresis with UV detection was described for the determination of doxorubucin and doxorubicinol in human plasma. After sample pretreatment, field-amplified sample stacking method was applied for sensitive improvement. The sample was employed with an electrokinetic injection of 10 kV for 30 sec. The capillary electrophoresis separation of do...

The classical theory of electrokinetic phenomena is based on the mean-field approximation that the electric field acting on an individual ion is self-consistently determined by the local mean charge density. This paper considers situations, such as concentrated electrolytes, multivalent electrolytes, or solvent-free ionic liquids, where the mean-field approximation breaks down. A fourth-order m...