BACKGROUND The cellular apoptosis susceptibility (CAS) protein is regarded as a proliferation-associated protein that associates with tumour proliferation as it associates with microtubule and functions in the mitotic spindle checkpoint. However, there is no any actual experimental study showing CAS (or CSE1 and CSE1L) can increase the proliferation of cancer cells. Previous pathological study ...

CAS is a docking protein, which was shown to act as a mechanosensor in focal adhesions. The unique assembly of structural domains in CAS is important for its function as a mechanosensor. The tension within focal adhesions is transmitted to a stretchable substrate domain of CAS by focal adhesion-targeting of SH3 and CCH domain of CAS, which anchor the CAS protein in focal adhesions. Mechanistic ...

"Etude etiologique de la circulation ra.pide iutra-rena-le"  Le but de l'angiographle renale n'est pas '.seu­lement le controle anatomique de l'organe, une etude physiologique (Hemodynamique) doit toujours etre prise en consideration.  Le temps normal de la circulation intra-renale selon les differents auteurs varie entre 6 a 8, 8 a 10 et 10 a 12 secondes, mais le temps moyen est de 6 a 8 seco...

Sodium saccharin and sodium ascorbate are known to promote urinary bladder carcinogenesis in rats following initiation with N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide (FANFT) or N-butyl-N-(4-hydroxybutyl) nitrosamine. Sodium salts of other organic acids have also been shown to be bladder tumor promoters. In addition, these substances increase urothelial proliferation in short term assays in r...

Résumé Les poumons reçoivent la totalité du drainage veineux du corps expliquant la grande fréquence des métastases pleuro-pulmonaires de plusieurs cancers. L'objectif était d'étudier les manifestations radio-cliniques des métastases pleuro-pulmonaires des cancers extra-thoraciques. Nous rapportons une étude rétrospective de patients porteurs de métastase pleuro-pulmonaire colligés dans notre s...

Most of cerebral aneurysms (CAs) are incidentally discovered without any neurological symptoms and the risk of rupture of CAs is relatively higher in Japanese population. The goal of treatments for patients with CAs is complete exclusion of the aneurysmal rupture risk for their lives. Since two currently available major treatments, microsurgical clipping and endovascular coiling, have inherent ...

salmonella enterica serovar typhimurium and s.enterica serovar enteritidis are the most frequently isolated serovars from food-borne diseases throughout the world. according to their antigenic profiles, salmonella shows different disease syndromes and host specificities. it is necessary and important to discriminate salmonella serovars from each other in order to ensure that each pathogen and i...

serologic diagnostic of hydatid cyst by immuno-fluorescence technique of the serological methods for the diognosis of hydatid cystimmuno-fl uoresccnt technique using fro zen section of the sco lex as antigen has given encouraging results. in t he present study examina t io n o f 8 5 sera correspond ing to h yd atido se patien ts by t his met hod, has shown th at 94% of th e cas es can be d e te...

1. Nous pouvons trouve une correlation precise entre les dosage de la renine et les aspects angiographiques uniquement dans les cas d'hypertension arterielle nephro­vasculaire·. 2. Cette correlation est importante pour deci. <l_er d'une="" intervention="" chirurgicale="" surtout="" en="" cas="" de="" lesion="" monolaterales,qui="" datent="" peu="" temps="" et="" qui="" ont="" valeurs="" ren...