A serious Mosquito borne yellow fever is one of the grave diseases which affect the major population. Since there is no specific treatment for yellow fever, there is a necessity to develop an effective agent. The series of acridinone analogues 3 to 5 were synthesized with help of non-conventional microwave heating and confirmed by respective spectral characterization. 5c and 3b showed highest a...

Content Synthetic scheme of phosphoramidite 9b ------------------------------------------------------------------S3 Figure S1 ------------------------------------------------------------------------------------------------------S4 Figure S2 ------------------------------------------------------------------------------------------------------S4 Figure S3 -----------------------------------------...

Allylated biphenol neolignans contain a variety of chemopreventive entities that have been used as anti-tumor drug leads. Herein, 37 allylated biphenols were evaluated for anti-proliferative activity by the MTT assay and inhibitory effect on the migration and tube formation of HUVECs featuring anti-angiogenic properties. 3-(2-Methylbut-3-en-2-yl)-3′,5′-bis(trifluoromethyl)-[1,1′-biphenyl]-4-ol ...

The structure activity relationships of 1H-benzimidazole-8-carboxylic acids (9a-9f), 1H-benzimidazole-8carboxylates (8a-8f) are described. Characteristic compounds showed improved demanding activity over a previously recognized 2-aminobenzimidazole series. In the lead optimization process and structure–activity relationship (SAR) of separate inhibitors based on modification of the lead molecule...

Treatment o f C[B(OMe)J4 with four equivalents o f a (rerr-phosphine)gold(I) chloride LAuCl with L = P (oC 6H n)3 or (2-MeC6H4)3P in the presence o f CsF in hexamethylphosphoric triamide (HMPT) affords the first complexes o f the type (LAu)4C. The product is formed to­ gether with salts (LAu)5C +BF4_ as the by-product for L = tricyclohexylphosphine, from which it can be separated by fractional ...

The influence of discharge rate, ambient temperature, and phase change material on the maximum temperature highest difference was investigated. battery tested with without under extreme rates (4C 5C) temperatures (310 K 320 K). Results showed that a reduced from 327.94 to 306.45 for 14.6 Ah lithium-ion discharged at 5C-rate K. Quantitatively determined parameter effects revealed PCM considerabl...