As of March 2001, 29 U.S. states had provided enhanced sanctions for high-BAC impaired driving offenders. Minnesota’s high-BAC statute, implemented in 1998, resulted in more severe case dispositions for high-BAC offenders than for other offenders. Overall dispositions for first and repeat offenders were more severe after the law, and the rate of alcohol test refusals was stable. The effective i...

The popular notion that alcohol intoxication enhances perceptions of the physical attractiveness of the opposite sex has been inconsistently supported. The current study tested intoxicated and non-intoxicated persons of both genders in naturalistic settings after measuring their blood alcohol concentration (BAC) by a breath test. A sample of 80 heterosexual university student social drinkers wa...

This article reviews the history of blood alcohol concentration (BAC) estimation training, which trains drinkers to discriminate distinct BAC levels and thus avoid excessive alcohol consumption. BAC estimation training typically combines education concerning alcohol metabolism with attention to subjective internal cues associated with specific concentrations. Estimation training was originally ...

A t present, human bronchioloalveolar carcinoma (BAC) is a disease with an evolving definition. The clinical concept of BAC needs to be re-evaluated with careful attention to the 2004 World Health Organization (WHO) criteria [1] due to major clinical implications. Series published in the literature before 2000, i.e. before the WHO definition of BAC, had not discerned a specific survival advanta...

The genome of the Bacterial Artificial Chromosome (BAC) transgenic mouse model of Huntington’s Disease (BAC HD) contains the 170 kb human HTT locus modified by the addition of exon 1 with 97 mixed CAA-CAG repeats. BAC HD mice present robust behavioral deficits in both the open field and the accelerating rotarod tests, two standard behavioral assays of motor function. BAC HD mice, however, also ...

Hierarchical genome assembly can be divided into three distinct stages: sequencing and assembling shotgun reads for each of a series of selected BAC clones; assembling the resulting fragments into BAC consensus sequences; and mapping and orienting the BAC consensus according to external positional information. We report a new approach for BAC consensus assembly that relies on iterative layouts ...

Abstract Background The percentage of the multidrug resistant Klebsiella pneumoniae clinical isolates is increasing worldwide. excessive exposure K. to sublethal concentrations biocides like benzalkonium chloride (BAC) in health care settings and communities could be one causes contributing global spread antibiotic resistance. Results We collected 50 these were daily exposed gradually BAC. cons...

The National Transportation Safety Board recently recommended that states establish a per se blood alcohol concentration (BAC) limit of 0.05 or lower for all drivers who are not already required to adhere to lower BAC limits in a national effort to reduce alcohol-impaired driving. There is strong evidence for adopting this recommendation. A comprehensive review of the literature on BAC limits w...

Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominant disorder with progressive degeneration of cerebellar Purkinje cells (PCs) and other neurons caused by expansion of a glutamine (Q) tract in the ATXN2 protein. We generated BAC transgenic lines in which the full-length human ATXN2 gene was transcribed using its endogenous regulatory machinery. Mice with the ATXN2 BAC transgene with an...