نتایج جستجو برای: قرمز اسیدی 206
تعداد نتایج: 21986 فیلتر نتایج به سال:
BACKGROUND A critical mechanism in atrial fibrillation (AF) is cardiac autonomic nerve remodeling (ANR). MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression at the post-transcriptional level. Numerous miRNAs are involved in diseases of the nervous and cardiovascular systems. OBJECTIVE We aimed to assess the underlying role of miRNAs in regulating cardiac ANR in AF by ri...
MicroRNA-206 (miR-206), the homolog of which in mice is termed miR-206-3p, is a muscle-specific miRNA known to be important in the development of skeletal muscle, and is involved in smooth muscle innervation of the airway through the post‑transcriptional suppression of brain‑derived neurotrophic factor (Bdnf). miR‑206‑3p is also expressed at significant levels in adult and embryonic skin; howev...
پایان نامه حاضر شامل پنج فصل است: در فصل اول به بررسی کلیات نگهداری و تعمیرات پرداخته شده است. در فصل دوم پیرامون روش انجام نگهداری و تعمیرات وسایل نقلیه هوایی و روش جاری تعمیرات بحث شده است. در فصل سوم به معرفی هلیکوپتر 206 پرداخته و تمام چکها و بازرسی های دیکته شده و عیوب پیش آمده برای 8 هلیکوپتر لیست شده است. نهایتا در فصل آخر به ارائه پیشنهادات و نتیجه گیری پرداخته شده است.
MicroRNAs are endogenous short chain nucleotide RNAs that regulate gene function by direct binding of target mRNAs. In this study, we investigated the effects of microRNA-206 (miR-206) on the development of gastric cancer. miR-206 was first confirmed to be downregulated in gastric cancer specimens. Conversely, upregulation of c-Met was confirmed in tissue samples of human gastric cancer, with i...
microRNAs have been implicated in mediating key aspects of skeletal muscle development and responses to diseases and injury. Recently, we demonstrated that a synaptically enriched microRNA, miR-206, functions to promote maintenance and repair of the neuromuscular junction (NMJ); in mutant mice lacking miR-206, reinnervation is impaired following nerve injury and loss of NMJs is accelerated in a...
Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related mortality worldwide. Angiogenesis is the major hallmark in NSCLC. So, further elucidation of molecular mechanisms underlying the angiogenesis of NSCLC is urgently needed. Here, we found that microRNA-206 (miR-206) decreased the angiogenic ability in NSCLC via inhibiting the 14-3-3ζ/STAT3/HIF-1α/VEGF pathway. Briefly, 14-3...
BACKGROUND & AIMS The paradox of selective hepatic insulin resistance, wherein the insulin-resistant liver fails to suppress glucose production but continues to produce lipids, has been central to the pathophysiology of hepatosteatosis and hyperglycemia. Our study was designed to investigate the mechanism(s) by which microRNA-206 alleviates the pathogenesis of hepatosteatosis and hyperglycemia....
تریپس پیاز Thrips tabaci Lindeman یکی از آفات مهم طیف وسیعی از محصولات اقتصادی کشاورزی در بسیاری از مناطق دنیا می باشد. در استان لرستان لوبیا (Phaseolus vulgaris L.) یکی از مهم ترین میزبانهای گیاهی این آفت محسوب می شود. این تحقیق در سال 1393 و به منظور بررسی مقاومت ده ژنوتیپ لوبیا قرمز به تریپس پیاز در ایستگاه تحقیقات کشاورزی بروجرد استان لرستان انجام گرفت. در این تحقیق عکس العمل ده ژنوتیپ...
NFE2L2/NRF2 silencing-inducible miR-206 targets c-MET/EGFR and suppresses BCRP/ABCG2 in cancer cells
The nuclear factor (erythroid-derived 2)-like 2 (NFE2L2/NRF2) plays a critical role in the expression of multiple antioxidant and detoxifying enzymes. Herein, we provide evidence of the molecular links between NRF2 and oncogenic signaling hepatocyte growth factor receptor (HGFR/c-MET) and epidermal growth factor receptor (EGFR). Interfering RNA-induced stable inhibition of NRF2 in ovarian carci...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید