نتایج جستجو برای: محلههای ناحیة 1 منطقة 14 تهران

تعداد نتایج: 3001554  

2015
Tetsuhisa Otani Kenzi Oshima Akiyo Kimpara Michiko Takeda Uri Abdu Shigeo Hayashi

Stable localization of the signaling complex is essential for the robust morphogenesis of polarized cells. Cell elongation involves molecular signaling centers that coordinately regulate intracellular transport and cytoskeletal structures. In Drosophila bristle elongation, the protein kinase IKKε is activated at the distal tip of the growing bristle and regulates the shuttling movement of recyc...

2014
Takamasa Harada Jerome Irianto Avathamsa Athirasala Rocky Diegmiller P. C. Dave P. Dingal Irena L. Ivanovska Dennis E. Discher

Cell motility within adult animals underlies a wide range of critical processes, including trafficking in disease and tissue repair. Cells in the periphery of a tumor, for example, crawl through surrounding tissue and ECM to divide or metastasize into narrow vessels (Weinberg, 2006). Multipotent stem cells in the bone marrow likewise transmigrate into blood capillaries or other tissues far from...

2015
Koichiro Aya Masaaki Kobayashi Junmu Tanaka Hajime Ohyanagi Takayuki Suzuki Kenji Yano Tomoyuki Takano Kentaro Yano Makoto Matsuoka

japonicum, and a Web Resource Database, Ljtrans DB Koichiro Aya*, Masaaki Kobayashi, Junmu Tanaka, Hajime Ohyanagi, Takayuki Suzuki, Kenji Yano, Tomoyuki Takano, Kentaro Yano and Makoto Matsuoka Bioscience and Biotechnology Center, Nagoya University, Nagoya, 464-8601 Japan School of Agriculture, Meiji University, Kawasaki, 214-8571 Japan CREST, JST, Japan Tsukuba Division, Mitsubishi Space Soft...

2002
Kathryn A. Baker

If defined broadly, innovation can be seen as the business of science organizations. However, like most of the organizational literature, the innovation literature has largely focused on innovation in private sector business organizations. This literature may, nonetheless, have insights that can be used by the science organizations, both private and public. First, although science organizations...

2014
Markus Hildenbeutel Eric L. Hegg Katharina Stephan Steffi Gruschke Brigitte Meunier Martin Ott

Oxidative phosphorylation is a key process of cellular metabolism and takes place within mitochondria. The respiratory chain complexes in the inner membrane connect the transfer of electrons from reducing equivalents to the final electron acceptor oxygen with the establishment of a membrane potential, which is in turn used for ATP synthesis. Respiratory chain complexes thus contain sequentially...

2011
Ferran Feixas Jelle Vandenbussche Patrick Bultinck Eduard Matito Miquel Solà

Aromaticity is a property usually linked to the ground state of stable molecules. Although it is well-known that certain excited states are unquestionably aromatic, the aromaticity of excited states remains rather unexplored. To move one step forward in the comprehension of aromaticity in excited states, in this work we analyze the electron delocalization and aromaticity of a series of low-lyin...

2015
Mark L. Cohen Chae Kim Tracy Haldiman Mohamed ElHag Prachi Mehndiratta Termsarasab Pichet Frances Lissemore Michelle Shea Yvonne Cohen Wei Chen Janis Blevins Brian S. Appleby Krystyna Surewicz Witold K. Surewicz Martha Sajatovic Curtis Tatsuoka Shulin Zhang Ping Mayo Mariusz Butkiewicz Jonathan L. Haines Alan J. Lerner Jiri G. Safar

Genetic and environmental factors that increase the risk of late-onset Alzheimer disease are now well recognized but the cause of variable progression rates and phenotypes of sporadic Alzheimer’s disease is largely unknown. We aimed to investigate the relationship between diverse structural assemblies of amyloid-b and rates of clinical decline in Alzheimer’s disease. Using novel biophysical met...

2014
Nasir H. Bhanpuri Allison M. Okamura Amy J. Bastian

1 Department of Biomedical Engineering, The Johns Hopkins School of Medicine, Baltimore MD, USA 2 Kennedy Krieger Institute, Baltimore MD, USA 3 Department of Neuroscience, The Johns Hopkins School of Medicine, Baltimore MD, USA 4 Department of Biomedical Engineering, University of Southern California, Los Angeles CA, USA 5 Department of Mechanical Engineering, Stanford University, Stanford CA,...

2009
Yoshihisa Kaizuka Adam D. Douglass Santosh Vardhana Michael L. Dustin Ronald D. Vale

The Rockefeller University Press $30.00 J. Cell Biol. www.jcb.org/cgi/doi/10.1083/jcb.200809136 Cite by DOI: 10.1083/jcb.200809136 JCB 1 of 14 Correspondence to Ronald D. Vale: [email protected] Abbreviations used in this paper: APC, antigen-presenting cell; cSMAC, central SMAC; CTB, cholera toxin subunit B; GPI, glycosylphosphatidylinositol; ITAM, immunoreceptor tyrosine-based activation motif...

2013
Gopinath Sutendra Evangelos D. Michelakis

2 3, 2 01 4 Pulmonary arterial hypertension (PAH) is a vascular remodeling disease with a relentless course toward heart failure and early death. Existing PAH therapies, all of which were developed originally to treat systemic vascular diseases, cannot reverse the disease or markedly improve survival and are expensive. Although there has been a recent increase in the number of potential new the...

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