Pseudomonas aeruginosa is a nearly ubiquitous human pathogen, and infections can be lethal to patients with impaired respiratory and immune systems. Prior studies have established that strong loss-of-function mutations in the egl-9 gene protect the nematode C. elegans from P. aeruginosa PAO1 fast killing. EGL-9 inhibits the HIF-1 transcription factor via two pathways. First, EGL-9 is the enzyme...

Inactivated influenza virus vaccine prepared from a non-pathogenic influenza virus strain A/duck/Hokkaido/Vac-1/2004 (H5N1) from the virus library conferred protective immunity to chickens against the challenge of antigenically drifted highly pathogenic avian influenza virus (HPAIV), A/whooper swan/Hokkaido/1/2008 (H5N1). The efficacy of the vaccine was comparable to that prepared from genetica...

„Pontosan a növekedéselmélet az, amelyről beszélni akarok: önmagáért, az eredményeiért, lyukakért, amelyeket még be kell tömni … .” – mondta Robert M. Solow 1987-ben, Nobel-díjas előadása elején, és ez motivációja ennek tanulmánynak is. A modern úttörőinek tekinthető Bob Trevor Swan alapvető tanulmányai 66 évvel ezelőtt, 1956-ban jelentek meg. növekedési irodalom azóta elképesztően bővült. Ez i...

In this study, the possibility that coronal mass ejections (CMEs) may be observed in neutral Lyman-α emission was investigated. An observing campaign was initiated for SWAN (Solar Wind ANisotropies), a Lyman-α scanning photometer on board the Solar and Heliospheric Observatory (SOHO) dedicated to monitoring the latitude distribution of the solar wind from its imprints on the interstellar sky ba...

Tropical cyclone ocean–wave model interactions are examined using an ESMF – (Earth System Modeling Framework) based tropical cyclone (TC) version of the Coupled Ocean/Atmosphere Mesoscale Prediction System (COAMPS ). This study investigates Hurricane Ivan, which traversed the Gulf of Mexico (GOM) in September 2004. Several oceanic and wave observational data sets, including Acoustic Doppler Cur...

Last year Swan et al. (1) published a reanalysis of data from 61 studies originally compiled and analyzed by Carlsen et al. (2). Just prior to the appearance of the Swan et al. artide, we published a reanalysis in another journal (3). Regional differences were considered in both reanalyses, but we examined only the effect ofyear in the final models (fertility status was also considered in the i...

The scope of this work is knowledge management in the Semantic Web. Its contribution is the design, development, and characterisation of an application node architecture for the Semantic Web, called Swan. The core of the Swan architecture consists of an OWL knowledge base which is supplemented by a hybrid reasoning mechanism. Hybrid reasoning in Swan combines F-Logic and Description Logic reaso...

mobility or traffic overload conditions. We use the term " soft " real-time services to indicate that real-time sessions could be regulated or dropped due to mobility or excessive traffic overloading at mobile wireless routers. SWAN is designed to limit such conditions, however. A novel aspect of SWAN is that it does not require the support of a QOS-capable MAC. Rather, soft real-time services ...

Sir, Double-cuffed Tenckhoff's catheters has been widely used for continuous ambulatory peritoneal dialysis (CAPD). Various techniques of insertion have been described with placement of catheter tip downwards into the pelvis for maximal drainage. One of the well-known complications of CAPD is migration of the catheter tip out of the pelvis which leads to inadequate drainage and dialysis. The in...