Commercial chikungunya virus (CHIKV)-specific IgM detection kits were evaluated at the Centers for Disease Control and Prevention (CDC), the Public Health Agency of Canada National Microbiology Laboratory, and the Caribbean Public Health Agency (CARPHA). The Euroimmun Anti-CHIKV IgM ELISA kit had ≥ 95% concordance with all three reference laboratory results. The limit of detection for low CHIK ...

This paper distinguishes a rare subset of myeloid dendritic-like cells found in mouse spleen from conventional (c) dendritic cells (DC) in terms of phenotype, function and gene expression. These cells are tentatively named "L-DC" since they resemble dendritic-like cells produced in longterm cultures of spleen. L-DC can be distinguished on the basis of their unique phenotype as CD11bhiCD11cloMHC...

In 1997, the Robert W. Woodruff Foundation provided $5 million, through the CDC Foundation, for the Cooperative for Assistance and Relief Everywhere (CARE) International and the Centers for Disease Control and Prevention (CDC) to create a sustainable partnership in global health. The investment provided discretionary resources and an incentive for CARE and CDC to maximize each other's strengths...

1 Université Pierre et Marie Curie, Laboratoire de Physique Théorique de la Matière Condensée, CNRS UMR 7600, Tour 24, 2ième ét., 4, Place Jussieu, F 75252 Paris Cedex 05, France. 2 H. Niewodniczański Institute of Nuclear Physics, Polish Academy of Sciences, Division of Theoretical Physics, ul. Eliasza-Radzikowskiego 152, PL 31-342 Kraków, Poland. 3LIPN, CNRS UMR 7030, Institut Galilée Universi...

background following coronary artery bypass graft (cabg), patients are at high risk (3.2%-8.3%) for developing hospital-acquired pneumonia (hap) with mortality rate of 24% to 50%. some of routine features in patients undergoing cabg are similar to clinical criteria of center of disease control (cdc) for diagnosis of pneumonia. this may lead to over-diagnosis of pneumonia in these patients. obje...

The cardinal direction calculus (CDC) proposed by Goyal and Egenhofer is a very expressive qualitative calculus for directional information of extended objects. Early work has shown that consistency checking of complete networks of basic CDC constraints is tractable while reasoning with the CDC in general is NP-hard. This paper shows, however, if allowing some constraints unspecified, then cons...

Cdc25 phosphatases are key positive cell cycle regulators that coordinate cell divisions with growth and morphogenesis in many organisms. Intriguingly in C. elegans, two cdc-25.1(gf) mutations induce tissue-specific and temporally restricted hyperplasia in the embryonic intestinal lineage, despite stabilization of the mutant CDC-25.1 protein in every blastomere. We investigated the molecular ba...

Content-Defined Chunking (CDC) has been playing a key role in data deduplication systems in the past 15 years or so due to its high redundancy detection ability. However, existing CDC-based approaches introduce heavy CPU overhead because they declare the chunk cutpoints by computing and judging the rolling hashes of the data stream byte by byte. In this paper, we propose FastCDC, a Fast and eff...

BACKGROUND AND AIMS Increased evidence suggests a pro-atherogenic role for conventional dendritic cells (cDC). However, due to the lack of an exclusive marker for cDC, their exact contribution to atherosclerosis remains elusive. Recently, a unique transcription factor was described for cDC, namely Zbtb46, enabling us to selectively target this cell type in mice. METHODS Low-density lipoprotei...

Collecting duct carcinoma (CDC) is a kidney cancer subtype that is thought to arise from principal cells in distal parts of the collecting ducts. Some studies suggested an overlap of CDC with upper tract urothelial carcinoma (UTUC), making the pathological diagnosis challenging. Herein, we performed for the first time transcriptome sequencing of CDC and compared them to UTUC and renal cell carc...