Currently, limited molecular markers exist that can determine where in the spectrum of chronic myeloid leukemia (CML) progression an individual patient falls at diagnosis. Gene expression profiles can predict disease and prognosis, but most widely used microarray analytical methods yield lengthy gene candidate lists that are difficult to apply clinically. Consequently, we applied a probabilisti...

MOTIVATION Selecting a small number of relevant genes for accurate classification of samples is essential for the development of diagnostic tests. We present the Bayesian model averaging (BMA) method for gene selection and classification of microarray data. Typical gene selection and classification procedures ignore model uncertainty and use a single set of relevant genes (model) to predict the...

The organization of axonal projections from the basomedial nucleus of the amygdala (BMA) was examined with the Phaseolus vulgaris leucoagglutinin (PHAL) method in adult male rats. The anterior and posterior parts of the BMA, recognized on cytoarchitectonic grounds, display very different projection patterns. Within the amygdala, the anterior basomedial nucleus (BMAa) heavily innervates the cent...

Bayesian model averaging (BMA) can be seen as the optimal approach to any induction task. It can reduce error by accounting for model uncertainty in a principled way, and its usefulness in several areas has been empirically veri ed. However, few attempts to apply it to rule induction have been made. This paper reports a series of experiments designed to test the utility of BMA in this eld. BMA ...

OBJECTIVE To assess the prevalence of leukemia in a series of bone marrow aspiration (BMA) samples collected to confirm provisional diagnoses of acute idiopathic thrombocytopenic purpura (ITP) in children. DESIGN A retrospective cohort. SETTING All BMA reports at The Hospital for Sick Children, Toronto, Ontario (a tertiary care pediatric hospital), from January 1, 1984, to May 31, 1996, wer...

The eclectic problem solving methodology used by the British Medical Association (BMA) is described in this paper. It has grown from the daily need to respond to doctors' practical queries and incorporates reference to law, traditional professional codes, and established BMA policies-all of which must be regularly assessed against the benchmark of contemporary societal expectations. The two Jeh...

An error crept into Des Spence’s column about private health cover for BMA staff (BMJ 2013;347:f5199, doi:10.1136/bmj. f5199). The BMA’smedia office told Spence during his research for the article, “Private medical insurance is only offered to a very small number of the BMA’s most senior members of staff—directors in the senior managers group—as part of their remuneration package.” However, Spe...

Existing theoretical and empirical evidence on the determinants of students’ performance reveals a direct link between pre-primary education achievement test scores in primary school. Relying first-of-its-kind 2015 wave data from Programme International Student Assessment (PISA), present study analyses associations science broad set variables, including regressors that proxy education. Employin...