The notation and terminology used in this paper have been introduced in the following articles: [3], [19], [9], [10], [16], [20], [4], [5], [22], [23], [21], [1], [6], [17], [18], [2], [25], [26], [24], [15], [12], [13], [8], [14], and [7]. Let A be a non empty set, x be an element, and a be an element of A. Let us observe that (A 7−→ x)(a) reduces to x. Let A, B be non empty topological spaces...

Chlamydia is the most common bacterial sexually transmitted infection among men who have sex with men. Repeat infection following treatment with 1g azithromycin is common and treatment failure of up to 22% has been reported. This study measured the pharmacokinetics of azithromycin in rectal tissue in men following a single 1g dose to assess whether azithromycin reaches the rectal site in adequa...

A method has been developed for measuring proŽ les of aerosol mass on thin (480 1g/cm2) Apiezon-L coatedMylar Ž lms employed in rotating drum aerosol impactor samplers using the ion beam analysis technique scanning transmission ion microscopy (STIM). The greased Mylar Ž lms are excellent impaction substrates and possess excellent uniformity in projected density, making them an ideal substrate f...

OBJECTIVE To evaluate the effect of Khat-induced myocardial infarction (MI) in Yemen. METHODS One hundred and twenty patients with MI, admitted to Al-Thawra Hospital, Sana'a City, Yemen, during the year 2001 and 120 volunteer controls were collected for this study. On the other hand, we used 48 adult male rabbits for this study and divided it into 8 groups. Each group was consist of 6 animals...

Chagas disease is a neglected tropical disease caused by the flagellated protozoan Trypanosoma cruzi. The current drugs used to treat this disease have limited efficacy and produce severe side effects. Quinolines, nitrogen heterocycle compounds that form complexes with heme, have a broad spectrum of antiprotozoal activity and are a promising class of new compounds for Chagas disease chemotherap...

Purpose: To synthesize Mannich base imidazole derivatives, and evaluate their antimicrobial, nematicidal and larvicidal properties . Methods: Compounds 1a-g and 2a-g were prepared using a Mannich condensation method. The chemical structures of compounds 2a-g were confirmed by Fourier transform infrared spectroscopy (IR), proton nuclear magnetic resonance (H-NMR), carbon nuclear magnetic resonan...

Ticagrelor is the first reversible, direct-acting, potent P2Y12 receptor antagonist in management of acute coronary syndromes. It is rapidly absorbed and extensively metabolized. AR-C124910XX, the major active metabolite, antagonizes the P2Y12 receptor at approximately equal potency. The metabolism of ticagrelor to AR-C124910XX involves CYP3A4 and CYP3A5. CYP3A polymorphisms have been well docu...

AIMS The emergence of second generation (2G) biofuels is widely seen as a sustainable response to the increasing controversy surrounding the first generation (1G). Yet, sustainability credentials of 2G biofuels are also being questioned. Drawing on work in Science and Technology Studies, we argue that controversies help focus attention on key, often value-related questions that need to be posed...

For simplicity, we use the following convention: G is a group, a, b are elements of G, m, n are natural numbers, and p is a prime natural number. One can prove the following propositions: (1) If for every natural number r holds n 6= pr, then there exists an element s of N such that s is prime and s | n and s 6= p. (2) For all natural numbers n, m such that n | pm there exists a natural number r...