The European Union Registration, Evaluation, Authorization, and Restriction of Chemicals (REACH) Regulation (EC 1907/2006) places significant new obligations on the manufacturers or importers (M/Is) of chemicals in Europe. It also places new responsibilities on downstream users (DUs) of these chemicals i.e. those that purchase and use chemical products. In particular, for registered classified ...

Since the potential for contaminant bioremediation in steam treated subsurface environments has not been explored, the thermal remedial treatment of a gasoline spill at Lawrence Livermore National Laboratory’s (LLNL) Livermore site provided an opportunity to study microbial community changes in the subsurface environment. Many terrestrial microorganisms die or become metabolically inactive if h...

In our varicose vein center, on a trial basis, among the patients with asymptomatic calf deep vein thrombosis (CDVT) we carefully selected the patients for varicose vein surgery using the requirements as follows; 1) the patients had varicose veins with incompetent saphenous veins, 2) sequential examination including DUS confirmed stability and clinical insignificance of asymptomatic CDVT, 3) th...

BACKGROUND Drug users (DUs), a population that accounts for some of the fastest-growing human immunodeficiency virus (HIV) epidemics globally, lag behind other populations with regard to HIV-related outcomes. We evaluated the role of voucher incentives on linkage and retention in care among DUs in India. METHODS In this randomized clinical trial, 120 DUs who were aged ≥18 years, HIV-infected,...

BACKGROUND Metachromatic leukodystrophy (MLD) is an autosomal recessive disorder caused by deficiency in arylsulfatase A activity, leading to accumulation of sulfatide substrates. Diagnostic and monitoring procedures include demonstration of reduced arylsulfatase A activity in peripheral blood leukocytes or detection of sulfatides in urine. However, the development of a screening test is challe...

E-mail: [email protected] he use of diagnostic ultrasound (DUS) has become widespread, in labor rooms, private offices, emergency departments, and even the shopping mall,1,2 and is widely perceived as safe.2,3 Indeed, there has been no independently longestablished report that DUS is harmful. However, as a form of energy, DUS has the potential to have effects on living tissues, that is, bioeffe...