Airway mucus is a hallmark of respiratory syncytial virus (RSV) lower respiratory tract illness. Laboratory RSV strains differentially induce airway mucus production in mice. Here, we tested the hypothesis that RSV strains differ in pathogenesis by screening six low-passage RSV clinical isolates for mucogenicity and virulence in BALB/cJ mice. The RSV clinical isolates induced variable disease s...

Public organizations, including institutions in the U.S. criminal justice (CJ) system, have been rapidly releasing information pertaining to COVID-19. Even CJ typically reticent share information, like private prisons, released vital COVID-19 information. The boon of available pandemic-related data, however, is not without problems. Unclear conceptualizations, stakeholders’ influence on data co...

In the present paper we consider some examples relative to the Deligne-Simpson problem (DSP) which is formulated like this: Give necessary and sufficient conditions upon the choice of the p+ 1 conjugacy classes cj ⊂ gl(n,C), resp. Cj ⊂ GL(n,C), so that there exist irreducible (p+1)-tuples of matrices Aj ∈ cj , A1 + . . .+Ap+1 = 0, resp. of matrices Mj ∈ Cj , M1 . . .Mp+1 = I. By definition, the...

Truncated hemoglobins (trHbs) are widely distributed in bacteria and plants and have been found in some unicellular eukaryotes. Phylogenetic analysis based on protein sequences shows that trHbs branch into three groups, designated N (or I), O (or II), and P (or III). Most trHbs are involved in the O2/NO chemistry and/or oxidation/reduction function, permitting the survival of the microorganism ...

BACKGROUND The STTR treatment cascade provides a framework for research aimed at improving the delivery of services, care and outcomes of PLWH. The development of effective approaches to increase HIV diagnoses and engage PLWH in subsequent steps of the treatment cascade could lead to earlier and sustained ART treatment resulting in viral suppression. There is an unmet need for research applying...

It is of adaptive value for a plant to prepare its defenses when a threat is detected, and certain plant volatiles associated with insect damage, such as cis-jasmone (CJ), are known to switch-on defense metabolism. We used aphid and aphid parasitoid responses to Arabidopsis thaliana as a model system for studying gene expression and defense chemistry and its impact at different trophic levels. ...

We have tested serum samples from 24 patients with multifocal motor neuropathy (MMN) for reactivity to ganglioside GM1 and to Gal( β 1-3)GalNAc-bearing glycoproteins isolated from human peripheral nerve and from Campylobacter jejuni (Cj) serotype O:19. IgM anti-GM1 antibodies were detected by ELISA in 11 patients (45.8%) with MMN and in only one subject (4%) from the control group. Western blot...

Further Reading Geankoplis CJ (1993) Transport Processes and Unit Operations. New Jersey: PTR Prentice Hall. King CJ (1980) Separation Processes. New York:McGrawHill. Kister HZ (1992) Distillation Design. New York: McGraw-Hill. Seader JD and Henley EJ (1998) Separation Process Principles. New York: John Wiley. Stichlmair JG and Fair JR (1998)Distillation Principles and Practice. New York: Wiley...

1.16. Again, I’ll only do the triangle inequality. Let x = (a1, . . . , an), y = (b1, . . . , bn), z = (c1, . . . , cn) be three points in Rn, then there is some integer j, 1 ≤ j ≤ n where the max occurs, so that d∞(x, y) = |aj − bj |. Hence, d∞(x, y) = |(aj−cj)+(cj−bj)| ≤ |aj−cj |+|cj−bj | But, |aj−cj | ≤ max{|a1− c1|, . . . , |an − cn|} = d∞(x, z), since it is one of the terms occurring in th...

We recently have found that apolipoprotein E-deficient (Apoe(-/-)) mice with the C57BL/6 background develop type 2 diabetes when fed a Western diet for 12 weeks. In the present study we constructed multiple Apoe(-/-) mouse strains to find diabetes-related phenotyptic variations that might be linked to atherosclerosis development. Evaluation of both early and advanced lesion formation in aortic ...