objective: hypericum perforatum (st. john's wort) has long been used in traditional medicine to treat a variety of internal and external ailments. the present study was done to evaluate the immumodulatory potentials of the hydroalcoholic extract of h. perforatum. materials and methods: twenty male balb/c-mice were randomly allocated in two equal groups and immunized with sheep red blood ce...

over production of uric acid by xanthine oxidase (xo) causes gout. xo inhibitors for example allopurinol are the most important available anti gout drugs. medicinal herbs are available natural sources that may be useful for the treatment of gout. in this study the inhibitory activity of aqueous extracts of matricaria chamomilla l., hypericum perforatum l., fraxinus excelsior l., zea mays l., tr...

Frederick John Poynton was born at Kelston rectory, Bath, in 1869. On leaving Marlborough College he started his medical education at University College, Bristol, and continued it at St. Mary's Hospital where he won a scholarship in Anatomy and Physiology. He qualified in 1893, and rapidly showed the absorbing interest in children which largely determined his medical career. A disciple of Chead...

Extracts from Hypericum perforatum (St. John’s wort; Clusiaceae) are widely used for the treatment of mild to moderate depression. Four classes of constituents – hyperforins, hypericins, flavonoids, and xanthones – appear to contribute to the antidepressant activity. Interestingly, all four classes of secondary metabolites involve polyketide derivatives. Key reactions of their biosyntheses are ...

background: st. john’s wort (hypericum perforatum l.) is an important medicinal plant that has been widely used for its antidepressant properties. objective: in this study morphological characteristics variation of populations of h. perforatum were investigated. methods: in this study, different morphological characteristics of 25 h. perforatum populations in iran’s natural habitats were evalua...

This article aims to summarize the current state of knowledge on St. John's wort (Hypericum perforatum L.) which is one of the oldest and best investigated medicinal herbs. Dried alcoholic extracts are the most important preparations on the market although a variety of other preparations are available. Depressive disorders according to modern diagnostic standards are the best known and most wid...

Extracts of Hypericum perforatum L. (St John’s wort) are now successfully Abstract competing for status as a standard antidepressant therapy. Because of this, great effort has been devoted to identifying the active antidepressant compounds in the extract. From a phytochemical point of view, St John’s wort is one of the best-investigated medicinal plants. A series of bioactive compounds has been...