نتایج جستجو برای: ژن hoxb13
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prostate cancer has been shown to increase prostate cancer risk whereby the risk is influenced by: (1) the number of affected family members, (2) first degree affected relatives compared to those who are more distantly related, (3) the presence of early onset cancers in a pedigree (typically men diagnosed at or before age 55).5,6 Despite this recognized familial component, identification of hig...
Although prostate cancer is a disease of the elderly, its diagnosis is not uncommonly made in men younger than 55 years. Both ethnic, familial and genetic factors play a role in the early onset of prostate cancer, but the biology, particularly of low-grade prostate cancers detected at young age is not well understood. Autopsy studies have shown a high prevalence of Gleason score 6 prostate canc...
Malignant melanoma is a common and frequently lethal disease. Current therapeutic interventions have little effect on survival, emphasizing the need for a better understanding of the genetic, epigenetic, and phenotypic changes in melanoma formation and progression. We identified 17 genes that were not previously known to be silenced by methylation in melanoma using a microarray-based screen fol...
Persistent Inflammation and Angiogenesis during Wound Healing in K14-Directed Hoxb13 Transgenic Mice
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