Background Chagas disease, caused by the protozoan Trypanosoma cruzi, is endemic in Latin America and affects 10 million people worldwide. Approximately 12,000 deaths attributable to Chagas disease occur annually due to Chagas disease cardiomyopathy (CCC), an inflammatory cardiomyopathy presenting with heart failure and arrythmia; 30% of infected subjects develop CCC years after infection. Gene...

On June 7, 2016, the Computing Community Consortium (CCC) and Association for the Advancement of Artificial Intelligence (AAAI) hosted a roundtable discussion on Artificial Intelligence for Social Good. The following response is a summary of the roundtable discussions. A more thorough report will be published by the CCC later this summer, and available at http://cra.org/ccc/resources/ccc-led-wh...

We introduce the Casl Consistency Checker (CCC), a tool that supports consistency proofs in the algebraic specification language Casl. CCC is a faithful implementation of a previously described consistency calculus. Its system architecture combines flexibility with correctness ensured by encapsulation in a type system. CCC offers tactics, tactical combinators, forward and backward proof, and a ...

OBJECTIVE To investigated the relationship between epicardial fat volume (EFV) and coronary collateral circulation (CCC) in patients with stable coronary artery disease (CAD). METHODS The study population consisted of 152 consecutive patients with CAD who underwent coronary angiography and were found to have at least 95% significiant lesion in at least one major coronary artery. EFV was asses...

Countercurrent chromatography (CCC) is a generic term covering all forms of liquid–liquid chromatography that use a support-free liquid stationary phase held in place by a simple centrifugal or complex centrifugal force field. Biphasic liquid systems are used with one liquid phase being the stationary phase and the other being the mobile phase. Although initiated almost 30 years ago, CCC lacked...

Cytokine expression in a tumor microenvironment can impact both host defense against the tumor and tumor cell survival. In this study, we sought to clarify whether the cytokine gene expression profile could have clinical associations with ovarian cancer. We analyzed the expression of 16 cytokine genes (IL-1α, IL-1β, IL-2, IL-4, IL-5, IL-8, IL-10, IL-12p35, IL-12p40, IL-15, IFN-γ, TNF-α, IL-6, H...

The AOSD tools and methodologies have developed in a rapid speed in Java area. However, no matter how homologous .Net and Java are, AOP tools on .Net platform are still in experimental stage. The complex infrastructure and multi-language support make it hard to establish aspect-oriented programming on .Net. Microsoft provides Microsoft Intermediate Language(MSIL) to facilitate language implemen...

The dispersion behavior of solutes was investigated in a rotating flowing coiled tube. Potassium iodide, tartrazine, ascorbic acid, lysozyme, bovine serum albumin (BSA), and silver nanoparticle (AgNPs) samples were eluted in a coiled tube of counter-current chromatography (CCC) apparatus with a single phase. Apparent convection peaks of low-diffusivity solutes appeared in the static CCC tube, w...

Clear cell carcinoma (CCC) of the ovary is known to show poorer sensitivity to chemotherapeutic agents and to be associated with a worse prognosis than the more common serous adenocarcinoma or endometrioid adenocarcinoma. To improve the survival of patients with ovarian CCC, the deeper understanding of the mechanism of CCC carcinogenesis as well as the efforts to develop novel treatment strateg...