Crimean-Congo haemorrhagic fever (CCHF) is a viral zoonotic disease with a high mortality rate in humans. The CCHF virus is transmitted to humans through the bite of Ixodid ticks or contact with blood or tissues of CCHF patients or infected livestock. In December 2008, a re-emerging outbreak of CCHF occurred in the southern part of Iran. Five people were hospitalised with sudden fever and haemo...

Crimean-Congo Hemorrhagic Fever (CCHF) is a life threatening acute viral infection characterized by fever, bleeding, leukopenia and thrombocytopenia. It is a major emerging infectious diseases threat, but its pathogenesis remains poorly understood and few data exist for the role of apoptosis in acute infection. We aimed to assess apoptotic gene expression in leukocytes in a cross-sectional coho...

BACKGROUND In this study, we aimed to determine knowledge levels regarding Crimean-Congo hemorrhagic fever (CCHF) among emergency healthcare workers (HCWs) in an endemic region. METHODS A questionnaire form consisting of questions about CCHF was applied to the participants. RESULTS The mean age was 29.6 ± 6.5 years (range 19 - 45). Fifty-four (49.5%) participants were physicians, 39 (35.8%)...

Ticks are vectors of some important arthropod-borne diseases in both fields of veterinary and medicine, such as Lyme, tularemia, Rocky Mountain spotted fever, and some types of encephalitis as well as Crimean Congo hemorrhagic fever (CCHF). Iran is known as one of the main foci of CCHF in west of Asia. This study was conducted in DarrehShahr County because of the development of animal husbandry...

BACKGROUND The relationship of changes in the peripheral blood lymphocyte subgroups during Crimean-Congo hemorrhagic fever (CCHF) to prognosis has not been reported. OBJECTIVES To determine peripheral blood lymphocyte subgroups in CCHF patients at the time of diagnosis and relate these to clinical outcome. STUDY DESIGN Peripheral blood samples were obtained from the patients treated at the ...

Crimean Congo hemorrhagic fever (CCHF) has the most extensive geographic distribution of the medically significant tick-borne viruses. Its causative agent is a negative-sense, single-stranded RNA virus belonging to the family Bunyaviridae, genus Nairovirus. The virus can be transmitted mainly through direct contact with blood or tissues from infected livestock or through bites of Hyalomma ticks...

Background: Liver stiffness in patients with chronic congestive heart failure (CCHF) is poorly understood and liver ultrasound transient elastography (LUTE) a new non-invasive method to detect this condition. In cross-sectional study we explored secondary hepatopathy CCHF detected by LUTE.

To the Editor: Crimean-Congo hemorrhagic fever (CCHF) was first described in Crimea in 1944 and in the Congo in 1969. Since then, many cases in humans have been reported from different regions (1–3). The disease is transmitted to humans through the bite of an infected tick or by direct contact with blood or tissue from infected humans and livestock. We report an unusual case of acute subdural h...

Sir Crimean-Congo Hemorrhagic Fever (CCHF) is an acute, tick-borne viral, zoonotic disease with hemorrhagic manifestations and considerable mortality in humans. It was first observed in Crimea in 1944 and was first isolated in Africa (Congo) from a febrile patient in 1956. The virus is widely distributed around the world (1, 2). CCHF is caused by an RNA virus. This virus has been classified as ...