In an attempt to study the biological activities of flavonoids, a flavone, flavanone and series of chalcones were synthesized and characterized by IR and 1 H NMR and elemental analysis. All the targeted compounds were screened for their antibacterial activity against Bacillus cereus, Enterococcus faecalis, Kleibsiella pneumonia and Pseudomonas aeroginosa and antifungal activity against Aspergil...

Doogh is the most popular and commonly consumed yoghurt-based Iranian drink. The aim of this study was to investigate the antibacterial effects of Ziziphora clinopodioides essential oil (ZEO) at 0.10 and 0.20% concentrations, nisin at 250 and 500 IU mL-1, and their combination against Salmonella typhimurium and Staphylococcusaureus in doogh during storage a...

The activity of four recombinant human cytokines on porcine neutrophils was evaluated. Porcine neutrophils were treated with varying doses of recombinant human tumour necrosis factor-alpha (rHu-TNF), interferon-gamma (rHu-IFN), interleukin-8 (rHu-lL-8), or granulocyte-macrophage colony-stimulating factor (rHu-GM-CSF). The function of treated neutrophils was compared with that of non-treated con...

Chronic Helicobacter pylori disease is reduced with Allium vegetable intake. This study was designed to assess the in vivo anti-H. pylori potential of a variety of garlic substances. The garlic materials all showed substantial but widely differing anti-H. pylori effects against all strains and isolates tested. The MICs (range, 8 to 32 microg/ml) and minimum bactericidal concentrations (MBCs) (r...

During a survey for bladder cancer in a healthy male population a surprisingly high incidence of significant microhaematuria was found and no urinary sample was completely free of blood. A study of the sensitivity of the different techniques for assessing microhaematuria seemed necessary. A semiquantitative centrifugation technique, developed for cytological purposes, was found to be the most s...

Objective—Tumor necrosis factor(TNF) has been linked to obesity-related insulin resistance and impaired endothelium-dependent vasodilatation, but the mechanisms have not been elucidated. To investigate whether TNFdirectly impairs insulin-mediated vasoreactivity in skeletal muscle resistance arteries and the role of c-Jun N-terminal kinase (JNK) in this interference. Methods and Results—Insulin-...

A large urban epidemic of dengue fever occurred in Kollam city of Kerala in 2003. During this epidemic, a study was conducted among 250 IgM dengue antibody-confirmed cases admitted to three major hospitals in Kollam city. The presenting symptoms were: fever (96.8%), headache (77.2%), abdominal pain (62.4%), diarrhoea (15.2%), bleeding (15.2%), skin rash (13.2%), pruritus (10.4%), sore throat (5...

The purpose of the study was to determine the microorganism species dependently on somatic cell count (SCC) in foremilk (inflammatory secretion) samples. Bacteriological examinations of 18 713 samples taken from clinically and subclinically (CMT positive) inflamed quarters were performed according to standard methods. Above 13% of the samples originated from quarters previously treated with ant...