In computer-participative multimedia applications, the computer not only manipulates media, but also digests it and performs independent actions based on media content. In this report I discuss an approach to the design of environments to support the development of computer-participative multimedia applications and I describe the implementation of the VuSystem, a computer-participative multimed...

Romiplostim, a thrombopoietin-mimetic peptibody, increases and maintains platelet counts in adults with immune thrombocytopenia (ITP). In this first study of a thrombopoietic agent in children, patients with ITP of ≥ 6 months' duration were stratified by age 1:2:2 (12 months-< 3 years; 3-< 12 years; 12-< 18 years). Children received subcutaneous injections of romiplostim (n = 17) or placebo (n ...

BACKGROUND AND PURPOSE CMBs have become increasingly recognized with the widespread use of MR imaging techniques that are sensitive to iron deposits. The purpose of this study was to correlate the presence of CMBs and carotid plaque characteristics. MATERIAL AND METHODS Seventy consecutive patients (47 men; 23 women; mean age, 65 years) were prospectively analyzed. Carotid arteries were studi...

0019-1035/$ see front matter 2009 Elsevier Inc. A doi:10.1016/j.icarus.2009.12.013 * Corresponding author. Fax: +1 617 496 6958. E-mail address: [email protected] (M. Ćuk). Multiple impact basins formed on the Moon about 3.8 Gyr ago in what is known as the lunar cataclysm or Late Heavy Bombardment. Many workers currently interpret the lunar cataclysm as an impact spike primarily caused by mai...

In this paper, area preserving multi-scale representations of planar curves are described. This allows smoothing without shrinkage at the same time preserving all the scale-space properties. The representations are obtained deforming the curve via geometric heat flows while simultaneously magnifying the plane by a homethety which keeps the enclosed area constant. When the Euclidean geometric he...

The aim of this study is to determine whether stereotactic body radiotherapy for multiple vertebral metastases treated with a single isocenter results in greater intrafraction errors than stereotactic body radiotherapy for single vertebral metastases and to determine whether the currently used spinal cord planning organ at risk volume and planning target volume margins are appropriate. Intrafra...

BACKGROUND/AIMS Diabetic patients usually require more medications than their nondiabetic counterparts. This work examined the effect of hyperglycemia on the pharmacokinetic properties of cyclosporine in a diabetic dog model. MAIN METHODS Diabetes was induced using a streptozotocin/alloxan combination and verified by measuring the serum glucose level. Cyclosporine was administered as a bolus ...

0019-1035/$ see front matter 2010 Elsevier Inc. A doi:10.1016/j.icarus.2010.11.014 ⇑ Corresponding author. E-mail address: [email protected] (C.I. Fas The geological record of early Mars displays a variety of features that indicate fundamental differences from more recent conditions. These include evidence for: (1) widespread aqueous alteration and phyllosilicate formation, (2) the existe...

0019-1035/$ see front matter 2010 Elsevier Inc. A doi:10.1016/j.icarus.2010.03.019 * Corresponding author. ** Corresponding author. Fax: +1 617 253 2350. E-mail addresses: [email protected] (I. Bertsatos), m Photoclinometry is the most common method used to obtain high-resolution topographic maps of planetary terrain. We derive the likelihood function of photoclinometric surface slope from (1) t...