In the title compound, C(23)H(21)FN(6)O, the dihedral angle between the fluoro-phenyl and pyrimidinone rings is 75.9 (1)°, and the dihedral angle between the methyl-phenyl and pyrazole rings is 40.3 (1)°. In the crystal structure, weak C-H⋯π(arene) and C-N⋯π(arene) inter-actions and intermolecular C-H⋯N and N-H⋯O hydrogen-bonding inter-actions are present.

In the title compound, C(21)H(16)F(2)N(2), the dihedral angle between the fluoro-phenyl groups is 66.34 (8)°, and the dihedral angle between the envelope-configured pyrazole group (N/N/C/C/C) and the benzene ring is 11.50 (9)°. The dihedral angles between the benzene and the two fluoro-substituted phenyl groups are 77.7 (6) and 16.7 (5)°. Weak C-H⋯π interactions contribute to the stability of t...

An eight-step linear sequence for the preparation of two diastereomers an 8-fluoro-ABC-steroid building block was developed. Key step intramolecular Diels–Alder reaction intermediate o-quinodimethane formed from a benzocyclobutene substituted with 5-fluorohex-5-en-4-one chain. This side chain prepared 6-chlorohex-1-ene by bromofluorination, elimination HBr, Finkelstein and alkylation literature...

The asymmetric unit of the title 1:1 adduct, C(10)H(8)N(2)S·C(6)F(4)I(2), comprises a half-mol-ecule of 1,2,4,5-tetra-fluoro-3,6-diiodo-benzene, and half a 4-(pyridin-4-ylsulfan-yl)pyridine mol-ecule. The former is completed by crystallographic inversion symmetry, the latter by twofold symmetry, with the S atom lying on the rotation axis. The almost planar 1,2,4,5-tetra-fluoro-3,6-diiodo-benzen...

The unique properties of fluorine atom on nucleic acid backbone can offer stricking functional and structural features. In order to extend the biological applications L-type acid, we chemically incorporate fluoro-modification into 2′-position L-cytidine, obtain a series fluoro-modified L-DNAs/ L-RNAs. Our melting study indicates that 2′-fluoro-modification does not disrupt thermostabilities wil...

The title structure, 3C(2)H(7)N(4)O(+)·HFPO(3) (-)·FPO(3) (2-)·H(2)O, contains three independent 2-carbamoylguanidinium cations, one fluoro-phospho-nate, one hydrogen fluoro-phospho-nate and one water mol-ecule. There are three different layers in the structure that are nearly perpendicular to the c axis. Each layer contains a cation and the layers differ by the respective presence of the water...

The title compound, C21H11ClF6N2O3 (systematic name: 1-{4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}-3-(2,6-di-fluoro-benzo-yl)urea), is a benzoyl-urea pesticide. The dihedral angles between the central fluoro-benzene ring and the terminal di-fluoro-phenyl ring and chloro-phenyl ring system are 62.15 (5) and 88.03 (5)°, respectively. In the crystal, N-H⋯O hydrogen bonds link adjacent...

The mol-ecule of the title hydrazone derivative, C(14)H(11)FN(4)O(4), is nearly planar, with a dihedral angle between the benzene rings of 3.71 (7)°. The central ethyl-idenehydrazine N-N=C-C plane makes dihedral angles of 5.32 (10) and 9.02 (10)° with the 2,4-dinitro- and 3-fluoro-substituted benzene rings, respectively. An intra-molecular N-H⋯O bond generates an S(6) ring motif. In the crystal...

The crystal structure of the title compound, C(21)H(21)F(2)NO, shows that the compound exists in a twin-chair conformation with an equatorial orientation of the ortho-fluoro-phenyl groups on either side of the secondary amino group. The title compound is a 1-methyl-ated analog of 2,4-bis-(2-fluoro-phen-yl)-3-aza-bicyclo-[3.3.1]nonan-9-one; the two compound both exhibit the same stereochemistry ...

In the title compound, C(32)H(28)F(2)N(2)O(2), the tetra-hydro-pyridine ring adopts a distorted boat conformation. The two fluoro-phenyl groups are attached to the tetra-hydro-pyridine ring in a trans orientation. The dihedral angle between the planes of the fluoro-substituted rings is 57.0 (1)°. The amino group and carbonyl O atom are involved in intra-molecular hydrogen bonding. In the crysta...