This investigation evaluated regional differences in blood flow and oxygen consumption and their relationship in exercised muscle during recovery from exhaustive exercise. Five healthy men performed exhaustive one-legged cycling exercise. Positron emission tomography was used to measure blood flow, oxygen uptake, and oxygen extraction in the quadriceps femoris muscle before and after exercise. ...

To study the release of lactate from muscle and its relationship to the blood lactate concentration during and after intense bicycling, young men cycled at 5.5 W kg(-1) body mass for 2 min to exhaustion or stopped after 1 min (nonexhaustive ride). The leg's release of lactate during and after each ride was taken from the measured blood flow and lactate concentrations in arterial and femoral-ven...

Recently, we showed that L-arginine (L-Arg) supplementation could attenuate acute exercise-induced oxidative and inflammatory stress in aging rats. In this study, we investigate whether L-Arg supplementation protects cellular oxidative stress, inflammation, or the mitochondrial DNA 4834-bp large deletion (mtDNA4834 deletion) in 14-week-old young rats tissues during exhaustive exercise. Rats wer...

this study was conducted to compare of inflammatory markers response in serum and saliva of healthy men following an exhaustive exercise test. twenty two volunteer healthy men (aged 20-30 years and body fat 10-16%) in a quasi-experimental, single group design participated in bruce exercise test. serum and saliva samples were collected immediately before and after the exercise test. c-reactive p...

BACKGROUND/AIMS In vitro studies have shown that band-3 function is mainly regulated by its phosphorylation status. The main purpose of the study was to investigate whether band-3 phosphorylation status interferes with an exhaustive running exercise-related dysfunction of RBC deformability. METHODS Rats were divided into sedentary control (C) and exercise test (ET) groups. The ET group was di...

Background: Exercise stress was shown to increase oxidative stress in rats. It lacks reports of increased protection afforded by dietary antioxidant supplements against ROS production during exercise stress. We evaluated the effects of vitamin E supplementation on renal non-enzymatic antioxidants in young rats submitted to exhaustive exercise stress. Methods: Wistar rats were divided into three...

Temporary proteinuria occurring after exercise is a common finding, and is explained predominantly by alterations in renal hemodynamics. In this study, it was investigated whether nitric oxide (NO), which is known to be effective on renal hemodynamics and to increase during exercise, has a role in post-exercise proteinuria. At the first step of this study, the effect of acute nitric oxide synth...

The extent of platelet activation after exhaustive exercise remains under discussion. Previous studies have provided contrary data, probably due to differences in the methodologies and the enrolled subjects. In the present study a maximal treadmill exercise (TR) was used to test platelet activity and -reactivity in 13 healthy non-smoking men. Blood samples were taken after a 30min rest, immedia...

BACKGROUND Physical stress triggers the endothelium to release von Willebrand Factor (VWF) from the Weibel Palade bodies. Since VWF is a risk factor for arterial thrombosis, it is of great interest to discover determinants of VWF response to physical stress. We aimed to determine the main mediators of the VWF increase by exhaustive physical exercise. METHODS 105 healthy individuals (18-35 yea...