Both estrogen and hydrogen sulfide (H 2 S) inhibit the proliferation of vascular smooth muscle cells (SMCs) development atherosclerosis. In absence endogenous H S as occurred in CSE-knockout (KO) mouse, however, stimulates SMCs. The underlying mechanisms for this seemingly controversial effect are unclear. present study, we demonstrated that stimulatory on CSE-KO SMCs was suppressed by inhibito...

ABSTRACT Introduction Skeletal muscle injuries account for 10% to 50% of treadmill sports injuries. Insulin-like growth factor (IGF) is a family polypeptides with both insulin-like anabolic and growth-promoting effects. Sports play vital role in the recovery skeletal Objective The paper analyzes ability 1 (IGF-1) repair injury caused by exercise. Method We injected drugs under wound after exerc...

Background: Liver cirrhosis is one of the most significant causes death in many regions worldwide. This study aimed to assess correlation hemostatic and endocrine parameters with Child-Turcotte-Pugh (CTP) scoring patients non-alcoholic liver cirrhosis. Materials Methods: included 59 monitored for a gastroenterology clinic from January 2018 February 2019. The subjects were grouped according CTP ...

Aims-To determine the role of insulin-like growth factors (IGF) in the proliferation of tumour cells, by studying the mitogenic response to IGFs of three cell lines of differing phenotype established from both malignant rhabdoid and Wilms tumour, representing a range of cell types (GOS 4, G401, and T3/73).Methods-Production of IGF-II and IGF-I was measured by radioimmunoassay, and the presence ...

Dairy cows enter a period of energy insufficiency after parturition. In liver, this energy deficit leads to reduced expression of the liver-specific GH receptor transcript (GHR1A) and decreased GHR abundance. As a consequence, hepatic processes stimulated by GH, such as IGF-I production, are reduced. In contrast, adipose tissue has been assumed to remain fully GH responsive in early lactation. ...