Many recent studies have suggested that activation of the aryl hydrocarbon receptor (AhR) reduces immune responses, thus suppressing allergies and autoimmune diseases. In our continuing study on natural AhR agonists in foods, we examined the influence of 37 health food materials on the AhR using a reporter gene assay, and found that aqueous ethanol extracts of cassia seed and rosemary had parti...

The redox behaviour of two potential anticancer anthraquinones, 9,10-anthraquinone and 2-chloromethyl-9,10-anthraquinone was investigated in a wide pH range. Cyclic voltammetry based assay was developed for the assessment of the effect of medium, substituents, potential scan rate and number of scans on the voltammetric response of anthraquinones. The electrode reaction mechanism was suggested o...

The relationships between molecular structures and properties of anthraquinone dichroic dyes were studied and dyes with large solubilities and dichroic ratios were developed. The yellow anthraquinone dye behaves as a quencher of the coumarin dye, and the mixture has a large absorption coefficient without fluorescence. These technologies can enlarge the color reproduction area of three-layer gue...

Anthraquinones are an important class of naturally occurring biologically active compounds. In this study, anthraquinone derivative 1,3-dihydroxy-9,10-anthraquinone-2- carboxylic acid (DHAQC) (2) was synthesized with 32% yield through the Friedel-Crafts condensation reaction. The mechanisms of cytotoxicity of DHAQC (2) in human breast cancer MCF-7 cells were further investigated. Results from t...

Electrochemical reduction of O2 provides a clean and decentralized pathway to produce H2O2 compared the current energy-intensive anthraquinone process. As electrochemical pro...

Kinetic energy distributions of ejected from a polyatomic molecule, anthraquinone, subjected to 60 fs, 800 nm laser pulses of intensity between 0.2 and 4.0 x 10(14) W x cm(-2), reveal field-driven restructuring of the molecule prior to Coulomb explosion. Calculations demonstrate fast intramolecular proton migration into a field-dressed metastable potential energy minimum. The proton migration o...

An 18 year old girl presented with a leiomyosarcoma of the small bowel with widespread dissemination. Despite short term remissions after chemotherapy and surgery she died of the disease 10 months later. A history of prolonged exposure to danthron (an anthraquinone laxative) in childhood was obtained. Anthraquinones are known to be mutagenic and may be carcinogenic in experimental systems but d...

This work deals with the development of ultra-thin film nanosensors for selective and sensitive detection toxic Hg2+ cations in aqueous media. 1,8-Bis[(2-aminoethyl)amino]anthraquinone D0 was functionalized by alkoxy groups different length to prepare ligands D3 D12 linear arrangement two polyamine receptors lipophilic alkyl chains. Chemosensor only binds copper(II) mercury(II) water/methanol (...

Anthraquinone (AQ) derivatives with relatively high reduction potentials have been synthesized to afford good candidates for electron transfer studies in DNA. Electron withdrawing groups on the anthraquinone ring gave derivatives with less negative reduction potentials. The anthraquinone imide (AQI) derivatives had reduction potentials less negative than AQ derivatives. The AQI ring system was ...