The title compound, C(25)H(22)N(2)O(3), was synthesized by the reaction of 3-nitro-benzaldehyde, dimedone and 2-naphthyl-amine in ethanol. In the mol-ecular structure, the cyclo-hexenone ring adopts an envelope conformation, whereas the piperidine ring has a boat conformation. The crystal packing is stabilized by inter-molecular N-H⋯O hydrogen bonds.

In the title compound, C(11)H(5)N(3)O(4), the nitro group is rotated by 29.91 (16)° out of the plane of the adjacent aryl ring. The 1,3-benzodioxole ring is nearly planar, with a maximium deviation of 0.0562 (10) Å. The dioxolene ring adopts an envelope conformation on the O-C-O C atom. In the crystal, mol-ecules are linked via C-H⋯O inter-actions, resulting in R(2) (2)(6) and R(2) (2)(12) grap...

A number of 1,3,4-oxadiazole, 3-9, and 1,2,4-triazole derivatives, 13-15, were synthesized starting form the acid hydrazide 1. The 1,3,4-thiadiazole derivative 12 was prepared from the substituted phenylthiosemicarbazide derivative 11 by treatment with sulfuric acid. The aryl hydrazone derivatives 10a-c were synthesized by reaction of the hydrazide 1 with the corresponding ketones. The thioalky...

The 1,3-dipolar cycloaddition reaction of (E)-7-arylidene-3-(1H-benzotriazol-1-yl)-6,7-dihydroindolizin-8(5H)-one and azomethine ylide which was generated in situ by the 11H-indeno[1,2-b]quinoxalin-11-one L-proline afforded novel 1'-aryl-3”-(1H-benzotriazol-1-yl)-5',5”,6',6”,7',7a'-hexahydro-1'H,8”H-dispiro[indeno[1,2-b]quinoxaline-11,3'-pyrrolizine-2',7”-indolizin]-8”-one moderate yields. stru...

The title compound, C(46)H(24)F(12)O(8)·C(4)H(8)O, consists of a cyclic aryl ester dimer and a tetra-hydro-furan mol-ecule. In the structure of the cyclic dimer, one carbonyl group stretches above the cavity and the other below.

Compounds containing aryl/heteroaryl acetic acid and aryl/heteroaryl ethylamine cores play important roles in the pharmaceutical field. Compounds containing aryl/heteroaryl acetic acid units form a large group of non-steroidal anti-inflammatory drugs such as Indomethacin [1], Diclophenac [2], Sulindac [3], Ketorolac [4], and many others. Also, this subunit appears in a number of antifungal [5],...